{"title":"Cellular \u0026 Energy Pathway Research","description":"\u003cp\u003eThis collection includes research peptides and formulations studied in laboratory models involving cellular pathway activity, bioenergetic processes, receptor pathway activity, and related biochemical systems.\u003c\/p\u003e\n\u003cp\u003eProducts in this collection may include individual research peptides, peptide blends, and oral research formulations. Each item is organized for research cataloging purposes only and is intended strictly for laboratory research use.\u003c\/p\u003e\n\u003cp\u003eThese products are not dietary supplements, medications, cosmetics, or consumer health products, and are not for human or veterinary use.\u003c\/p\u003e","products":[{"product_id":"cjc-1295-no-dac-ipamorelin-cjc-ipa","title":"CJC-1295 No DAC + Ipamorelin Research Peptide Blend – 5mg \/ 5mg","description":"\u003ch4 data-path-to-node=\"4\"\u003e\u003cstrong\u003eCJC-1295 No DAC \u0026amp; Ipamorelin Blend (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"5\"\u003e\u003cb data-path-to-node=\"5\" data-index-in-node=\"0\"\u003eSequence (CJC-1295 No DAC):\u003c\/b\u003e Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 \u003cb data-path-to-node=\"5\" data-index-in-node=\"150\"\u003eSequence (Ipamorelin):\u003c\/b\u003e Aib-His-D-2-Nal-D-Phe-Lys-NH2 \u003cb data-path-to-node=\"5\" data-index-in-node=\"203\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"5\" data-index-in-node=\"245\"\u003ePurity:\u003c\/b\u003e \u0026gt;99% (HPLC)\u003cbr\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"9\"\u003eThis premium lyophilized blend combines \u003cb data-path-to-node=\"9\" data-index-in-node=\"40\"\u003eCJC-1295 No DAC\u003c\/b\u003e (Modified GRF 1-29) and \u003cb data-path-to-node=\"9\" data-index-in-node=\"80\"\u003eIpamorelin\u003c\/b\u003e to create a synergistic research tool for the investigation of the Growth Hormone (GH) axis.\u003c\/p\u003e\n\u003cp data-path-to-node=\"10\"\u003eUnlike recombinant hGH, which bypasses the pituitary, this blend utilizes \u003cb data-path-to-node=\"10\" data-index-in-node=\"74\"\u003e\"Neuroendocrine Synergy\"\u003c\/b\u003e to amplify the body’s natural, pulsatile GH secretion. It pairs a chemically stabilized Growth Hormone-Releasing Hormone (GHRH) analog with a highly selective Growth Hormone Secretagogue (GHS) to maximize signal efficiency without significant impact on cortisol or prolactin levels.\u003c\/p\u003e\n\u003chr data-path-to-node=\"11\"\u003e\n\u003ch3 data-path-to-node=\"12\"\u003e\u003cb data-path-to-node=\"12\" data-index-in-node=\"0\"\u003eMechanism of Action: The Power of Synergy\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"13\"\u003eThe efficacy of this co-formulation relies on targeting two distinct receptors simultaneously. Research suggests that the combined effect is greater than the sum of its parts (1+1 \u0026gt; 2).\u003c\/p\u003e\n\u003ch4 data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003e1. CJC-1295 No DAC (The Amplifier)\u003c\/b\u003e\u003c\/h4\u003e\n\u003cul data-path-to-node=\"15\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"15,0,0\"\u003e\u003cb data-path-to-node=\"15,0,0\" data-index-in-node=\"0\"\u003eClass:\u003c\/b\u003e GHRH Analog (Tetrasubstituted)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"15,1,0\"\u003e\u003cb data-path-to-node=\"15,1,0\" data-index-in-node=\"0\"\u003eMechanism:\u003c\/b\u003e Binds to the GHRH receptor on the anterior pituitary.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"15,2,0\"\u003e\u003cb data-path-to-node=\"15,2,0\" data-index-in-node=\"0\"\u003eAction:\u003c\/b\u003e Stimulates the \u003cb data-path-to-node=\"15,2,0\" data-index-in-node=\"23\"\u003esynthesis\u003c\/b\u003e of growth hormone by increasing intracellular cAMP. It effectively increases the \"pool\" of GH available for release.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"15,3,0\"\u003e\u003cb data-path-to-node=\"15,3,0\" data-index-in-node=\"0\"\u003eEngineering:\u003c\/b\u003e This \"No DAC\" variant features four specific amino acid substitutions (Tetrasubstitution) that protect it from DPP-IV enzymatic cleavage, extending its biological activity to 30-60 minutes—ideal for mimicking natural physiological pulses.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003e2. Ipamorelin (The Trigger)\u003c\/b\u003e\u003c\/h4\u003e\n\u003cul data-path-to-node=\"17\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,0,0\"\u003e\u003cb data-path-to-node=\"17,0,0\" data-index-in-node=\"0\"\u003eClass:\u003c\/b\u003e Selective GH Secretagogue (GHS)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,1,0\"\u003e\u003cb data-path-to-node=\"17,1,0\" data-index-in-node=\"0\"\u003eMechanism:\u003c\/b\u003e Binds to the Ghrelin receptor (GHS-R1a).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,2,0\"\u003e\u003cb data-path-to-node=\"17,2,0\" data-index-in-node=\"0\"\u003eAction:\u003c\/b\u003e Triggers the immediate \u003cb data-path-to-node=\"17,2,0\" data-index-in-node=\"31\"\u003erelease\u003c\/b\u003e (exocytosis) of stored GH vesicles by depolarizing the somatotroph via calcium influx.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,3,0\"\u003e\u003cb data-path-to-node=\"17,3,0\" data-index-in-node=\"0\"\u003eSelectivity:\u003c\/b\u003e Unlike older generations (GHRP-6\/GHRP-2), Ipamorelin is highly selective. It stimulates GH release \u003cb data-path-to-node=\"17,3,0\" data-index-in-node=\"112\"\u003ewithout\u003c\/b\u003e spiking ACTH (cortisol) or prolactin, ensuring clean research data unconfounded by stress hormones.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"18\"\u003e\n\u003ch3 data-path-to-node=\"19\"\u003e\u003cb data-path-to-node=\"19\" data-index-in-node=\"0\"\u003eChemical Specifications\u003c\/b\u003e\u003c\/h3\u003e\n\u003ctable data-path-to-node=\"20\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eComponent\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eKey Modification\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,1,0,0\"\u003e\u003cb data-path-to-node=\"20,1,0,0\" data-index-in-node=\"0\"\u003eCJC-1295 No DAC\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,1,1,0\"\u003e~3367.9 Da\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,1,2,0\"\u003eC152H252N44O42\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp data-path-to-node=\"20,1,3,0\"\u003e\u003cb data-path-to-node=\"20,1,3,0\" data-index-in-node=\"0\"\u003eD-Ala (Pos 2):\u003c\/b\u003e Blocks DPP-IV degradation.\u003c\/p\u003e\n\u003cbr data-path-to-node=\"20,1,3,1\"\u003e\n\u003cp data-path-to-node=\"20,1,3,2\"\u003e\u003cb data-path-to-node=\"20,1,3,2\" data-index-in-node=\"0\"\u003eGln (Pos 8):\u003c\/b\u003e Prevents deamidation.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,2,0,0\"\u003e\u003cb data-path-to-node=\"20,2,0,0\" data-index-in-node=\"0\"\u003eIpamorelin\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,2,1,0\"\u003e~711.9 Da\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,2,2,0\"\u003eC38H49N9O5\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,2,3,0\"\u003e\u003cb data-path-to-node=\"20,2,3,0\" data-index-in-node=\"0\"\u003eAib \u0026amp; D-2-Nal:\u003c\/b\u003e Structural constraints for high GHS-R1a affinity and stability.\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003chr data-path-to-node=\"21\"\u003e\n\u003ch3 data-path-to-node=\"22\"\u003e\u003cb data-path-to-node=\"22\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e1. Musculoskeletal Regeneration \u0026amp; Hypertrophy\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe GH\/IGF-1 axis is a primary driver of protein synthesis via the mTOR pathway. This blend is frequently utilized in research regarding:\u003c\/p\u003e\n\u003cul data-path-to-node=\"24\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"24,0,0\"\u003eActivation of satellite cells for muscle fiber repair.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"24,1,0\"\u003eNitrogen retention in catabolic states (e.g., sarcopenia).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"24,2,0\"\u003eCollagen synthesis for tendon and ligament connective tissue integrity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e2. Lipolysis \u0026amp; Metabolic Regulation\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGrowth hormone is a potent lipolytic agent. Research indicates that the pulsatile release generated by this blend is superior for fat loss compared to continuous \"bleed\" methods (like DAC variants), which can desensitize receptors.\u003c\/p\u003e\n\u003cul data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eVisceral Fat:\u003c\/b\u003e Specific targeting of visceral adipocytes which have high GH receptor density.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,1,0\"\u003e\u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"0\"\u003eInsulin Sensitivity:\u003c\/b\u003e Pulsatile administration mitigates the risk of insulin resistance often seen with chronic GH elevation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e3. Neuroprotection \u0026amp; Sleep Architecture\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGHRH is inherently sleep-promoting. Investigational protocols suggest that administration prior to sleep cycles may reinforce Slow-Wave Sleep (Deep Sleep), facilitating neurocognitive recovery and repair.\u003c\/p\u003e\n\u003chr data-path-to-node=\"28\"\u003e\n\u003ch3 data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003eState:\u003c\/b\u003e Lyophilized (Freeze-Dried) Cake.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 24 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,0\"\u003e\u003cb data-path-to-node=\"30,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e Use Bacteriostatic Water (0.9% Benzyl Alcohol). Inject diluent slowly down the side of the vial to avoid foaming. \u003cb data-path-to-node=\"30,2,0\" data-index-in-node=\"130\"\u003eDo not shake.\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,3,0\"\u003e\u003cb data-path-to-node=\"30,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Once reconstituted, store at 4°C (Refrigerator). Use within 28 days for optimal stability.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp\u003eFOR RESEARCH USE ONLY.\u003c\/p\u003e\n\u003cp\u003eThis product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47709264478422,"sku":"2XB-CJCIPA-55","price":38.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/2X-Blend-CJC-1295-No-DAC-5mg-Ipamorelin-5mg.png?v=1768509803"},{"product_id":"aod-9604-tyr-hgh-177-191-research-peptide","title":"AOD 9604 Research Peptide – 6mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eAOD 9604 Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe \u003cb data-path-to-node=\"14\" data-index-in-node=\"74\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"116\"\u003eConfiguration:\u003c\/b\u003e Cyclic (Disulfide Bridge Cys7-Cys14) \u003cb data-path-to-node=\"14\" data-index-in-node=\"168\"\u003ePurity:\u003c\/b\u003e \u0026gt;99% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"188\"\u003eContent:\u003c\/b\u003e 6mg per vial\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eAOD 9604\u003c\/b\u003e (Advanced Obesity Drug) is a synthetic hexadecapeptide representing the C-terminal lipolytic domain of Human Growth Hormone (hGH residues 177-191).\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eOriginally developed to isolate the fat-burning properties of hGH from its insulin-antagonistic effects, this peptide features an N-terminal Tyrosine \"cap\" and a cyclic disulfide bridge. These modifications stabilize the molecular structure, allowing it to mimic the amphipathic alpha-helix of the native hormone. Research indicates it is a potent regulator of lipid metabolism and cartilage regeneration without stimulating IGF-1 or inducing hyperglycemia.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The \"Push-Pull\" Effect\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eAOD 9604 operates through a distinct non-hGHR pathway, exerting a specific influence on adipocytes and mesenchymal tissues.\u003c\/p\u003e\n\u003ch4 data-path-to-node=\"22\"\u003e\u003cb data-path-to-node=\"22\" data-index-in-node=\"0\"\u003e1. Metabolic Regulation (Fat Loss)\u003c\/b\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"23\"\u003eThe peptide utilizes a \"Push-Pull\" mechanism on adipose tissue:\u003c\/p\u003e\n\u003cul data-path-to-node=\"24\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"24,0,0\"\u003e\u003cb data-path-to-node=\"24,0,0\" data-index-in-node=\"0\"\u003eStimulation of Lipolysis (The Push):\u003c\/b\u003e It upregulates \u003cb data-path-to-node=\"24,0,0\" data-index-in-node=\"52\"\u003eBeta-3 Adrenergic Receptors (β3-AR)\u003c\/b\u003e on fat cells, enhancing the sensitivity to endogenous fat-burning signals.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"24,1,0\"\u003e\u003cb data-path-to-node=\"24,1,0\" data-index-in-node=\"0\"\u003eInhibition of Lipogenesis (The Pull):\u003c\/b\u003e It inhibits \u003cb data-path-to-node=\"24,1,0\" data-index-in-node=\"50\"\u003eLipoprotein Lipase (LPL)\u003c\/b\u003e and \u003cb data-path-to-node=\"24,1,0\" data-index-in-node=\"79\"\u003eAcetyl-CoA Carboxylase (ACC)\u003c\/b\u003e, preventing the uptake of dietary fat and the synthesis of new triglycerides.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e2. Musculoskeletal Regeneration\u003c\/b\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"26\"\u003eRecent investigations (Kwon et al.) have identified AOD 9604 as a chondroprotective agent.\u003c\/p\u003e\n\u003cul data-path-to-node=\"27\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"27,0,0\"\u003e\u003cb data-path-to-node=\"27,0,0\" data-index-in-node=\"0\"\u003eCartilage Repair:\u003c\/b\u003e In models of osteoarthritis, the peptide enhanced the synthesis of Collagen Type II and proteoglycans.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"27,1,0\"\u003e\u003cb data-path-to-node=\"27,1,0\" data-index-in-node=\"0\"\u003eSynergy with Hyaluronic Acid (HA):\u003c\/b\u003e When co-administered with HA, AOD 9604 demonstrated superior efficacy in reducing lameness and structural damage compared to either agent alone.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"28\"\u003e\n\u003ch3 data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003eChemical Specifications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003eMolecular Formula:\u003c\/b\u003e C78H123N23O23S2\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003eMolecular Mass:\u003c\/b\u003e 1815.1 Da\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,0\"\u003e\u003cb data-path-to-node=\"30,2,0\" data-index-in-node=\"0\"\u003eStructural Stability:\u003c\/b\u003e The disulfide bond between Cysteine 7 and Cysteine 14 creates a rigid cyclic loop essential for receptor recognition. The N-terminal Tyrosine protects against enzymatic degradation by aminopeptidases.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eSafety Profile \u0026amp; Selectivity\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"33\"\u003eAOD 9604 is distinguished by its high safety profile in research settings. Unlike full-length hGH, AOD 9604:\u003c\/p\u003e\n\u003cul data-path-to-node=\"34\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,0,0\"\u003e\u003cb data-path-to-node=\"34,0,0\" data-index-in-node=\"0\"\u003eDoes NOT release IGF-1:\u003c\/b\u003e Eliminating the risk of acromegaly or proliferative tissue growth.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,1,0\"\u003e\u003cb data-path-to-node=\"34,1,0\" data-index-in-node=\"0\"\u003eDoes NOT induce Insulin Resistance:\u003c\/b\u003e It has no effect on blood glucose or insulin sensitivity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,2,0\"\u003e\u003cb data-path-to-node=\"34,2,0\" data-index-in-node=\"0\"\u003eHigh Tolerability:\u003c\/b\u003e In human trials involving over 900 subjects, no anti-peptide antibodies or significant adverse events were reported.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"35\"\u003e\n\u003ch3 data-path-to-node=\"36\"\u003e\u003cb data-path-to-node=\"36\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"37\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"37,0,0\"\u003e\u003cb data-path-to-node=\"37,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"37,1,0\"\u003e\u003cb data-path-to-node=\"37,1,0\" data-index-in-node=\"0\"\u003eStorage (Lyophilized):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 24 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"37,2,0\"\u003e\u003cb data-path-to-node=\"37,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e Use Bacteriostatic Water (0.9% Benzyl Alcohol) or Sterile Saline. Inject diluent slowly to avoid foaming. \u003cb data-path-to-node=\"37,2,0\" data-index-in-node=\"122\"\u003eDo not shake.\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"37,3,0\"\u003e\u003cb data-path-to-node=\"37,3,0\" data-index-in-node=\"0\"\u003eStorage (Reconstituted):\u003c\/b\u003e Store at 4°C (Refrigerator). Use within 14-21 days.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"38\"\u003e\n\u003ch3 data-path-to-node=\"39\"\u003e\u003cb data-path-to-node=\"39\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"40\"\u003e\u003cb data-path-to-node=\"40\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47709709369558,"sku":"AOD9604-6","price":42.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/AOD-9604-6mg.png?v=1768514591"},{"product_id":"cjc-1295-no-dac-modified-grf-1-29-research-peptide","title":"CJC-1295 No DAC Research Peptide – 10mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eCJC-1295 No DAC (Modified GRF 1-29) Peptide\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 \u003cb data-path-to-node=\"14\" data-index-in-node=\"132\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"174\"\u003eClass:\u003c\/b\u003e Tetrasubstituted GHRH Analogue \u003cb data-path-to-node=\"14\" data-index-in-node=\"212\"\u003eHalf-Life:\u003c\/b\u003e ~30 Minutes (Pulsatile) \u003cb data-path-to-node=\"14\" data-index-in-node=\"247\"\u003ePurity:\u003c\/b\u003e \u0026gt;99% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"267\"\u003eContent:\u003c\/b\u003e Available in 5mg and 10mg vials\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eCJC-1295 No DAC\u003c\/b\u003e, scientifically known as \u003cb data-path-to-node=\"17\" data-index-in-node=\"41\"\u003eModified GRF 1-29\u003c\/b\u003e, is a rational engineering triumph in neuroendocrinology. It is a synthetic, tetrasubstituted analogue of the native Growth Hormone-Releasing Hormone (GHRH) 1-29 fragment.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eUnlike native GHRH, which is degraded within minutes, Modified GRF 1-29 incorporates four specific amino acid substitutions that render it resistant to enzymatic cleavage (DPP-IV) and chemical oxidation. This extends its biological half-life to approximately \u003cb data-path-to-node=\"18\" data-index-in-node=\"259\"\u003e30 minutes\u003c\/b\u003e. Crucially, because it lacks the Drug Affinity Complex (DAC), it preserves the \u003cb data-path-to-node=\"18\" data-index-in-node=\"349\"\u003enatural, pulsatile secretion\u003c\/b\u003e of Growth Hormone, avoiding the \"GH bleed\" and receptor desensitization associated with continuous long-acting analogs.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The Pulsatile Signal\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eModified GRF 1-29 acts as a selective agonist for the GHRH Receptor (GHRH-R) on pituitary somatotrophs.\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003ecAMP-PKA Pathway:\u003c\/b\u003e Binding triggers the Gs-protein cascade, increasing intracellular cAMP. This initiates both immediate vesicle release (secretion) and long-term gene transcription (synthesis via Pit-1).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eDPP-IV Resistance:\u003c\/b\u003e The substitution of \u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"39\"\u003eD-Alanine\u003c\/b\u003e at position 2 prevents the enzyme DPP-IV from cleaving the peptide, ensuring sustained receptor activation compared to native Sermorelin.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eSynergy:\u003c\/b\u003e It effectively \"loads the gun\" (synthesis), making it highly synergistic with Ghrelin mimetics (GHRPs) that \"pull the trigger\" (release).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eChemical Engineering: The 4 Modifications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003eThe \"Modified\" designation refers to four specific changes to the native sequence that optimize stability for research use:\u003c\/p\u003e\n\u003col start=\"1\" data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eTyr1-D-Ala2:\u003c\/b\u003e Confers resistance to DPP-IV digestion.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,1,0\"\u003e\u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"0\"\u003eGln8:\u003c\/b\u003e Replaces Asparagine to prevent deamidation and improve shelf-stability.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,2,0\"\u003e\u003cb data-path-to-node=\"26,2,0\" data-index-in-node=\"0\"\u003eAla15:\u003c\/b\u003e Replaces Glycine to stabilize the alpha-helical structure for better receptor binding.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,3,0\"\u003e\u003cb data-path-to-node=\"26,3,0\" data-index-in-node=\"0\"\u003eLeu27:\u003c\/b\u003e Replaces Methionine to prevent oxidation (sulfoxide formation) during storage.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003chr data-path-to-node=\"27\"\u003e\n\u003ch3 data-path-to-node=\"28\"\u003e\u003cb data-path-to-node=\"28\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003e1. Pulsatile GH Secretion\u003c\/b\u003e Research confirms that Modified GRF 1-29 amplifies the natural peaks of GH secretion without elevating the basal \"trough\" levels. This mimics youthful physiology and allows for receptor resensitization between pulses.\u003c\/p\u003e\n\u003cp data-path-to-node=\"30\"\u003e\u003cb data-path-to-node=\"30\" data-index-in-node=\"0\"\u003e2. Sleep Architecture (SWS)\u003c\/b\u003e GHRH is a potent somnogenic factor. Studies utilizing EEG monitoring indicate that administration prior to the sleep window enhances \u003cb data-path-to-node=\"30\" data-index-in-node=\"161\"\u003eSlow Wave Sleep (SWS)\u003c\/b\u003e and Delta wave power, which correlates with improved cognitive recovery and endogenous hormonal repair.\u003c\/p\u003e\n\u003cp data-path-to-node=\"31\"\u003e\u003cb data-path-to-node=\"31\" data-index-in-node=\"0\"\u003e3. Lipolysis (Fat Loss)\u003c\/b\u003e Through the pulsatile elevation of GH, Modified GRF 1-29 activates \u003cb data-path-to-node=\"31\" data-index-in-node=\"91\"\u003eHormone Sensitive Lipase (HSL)\u003c\/b\u003e in adipocytes. Research shows a preference for visceral adipose tissue reduction, mediated by the downregulation of PPAR-gamma.\u003c\/p\u003e\n\u003chr data-path-to-node=\"32\"\u003e\n\u003ch3 data-path-to-node=\"33\"\u003e\u003cb data-path-to-node=\"33\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"34\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,0,0\"\u003e\u003cb data-path-to-node=\"34,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,1,0\"\u003e\u003cb data-path-to-node=\"34,1,0\" data-index-in-node=\"0\"\u003eStorage (Lyophilized):\u003c\/b\u003e Store at -20°C (Freezer). Stable for \u0026gt;24 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,2,0\"\u003e\u003cb data-path-to-node=\"34,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"34,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,2,1,0,0\"\u003e\u003cb data-path-to-node=\"34,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Bacteriostatic Water or Sterile Saline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,2,1,1,0\"\u003e\u003cb data-path-to-node=\"34,2,1,1,0\" data-index-in-node=\"0\"\u003eSolubility:\u003c\/b\u003e Highly soluble (polar\/basic profile).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,3,0\"\u003e\u003cb data-path-to-node=\"34,3,0\" data-index-in-node=\"0\"\u003eStorage (Reconstituted):\u003c\/b\u003e Store at 4°C (Refrigerator). Use within 14-21 days. The Leu27 substitution significantly improves solution stability compared to native GHRH.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"35\"\u003e\n\u003ch3 data-path-to-node=\"36\"\u003e\u003cb data-path-to-node=\"36\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"37\"\u003e\u003cb data-path-to-node=\"37\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"10mg","offer_id":47709956112598,"sku":"CJC-NODAC-10","price":43.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/CJC-1295-No-DAC-10mg.png?v=1768509497"},{"product_id":"cjc-1295-with-dac-ghrh-research-peptide","title":"CJC-1295 with DAC Research Peptide – 10mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eCJC-1295 with DAC Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(Maleimidopropionic acid)-NH2 \u003cb data-path-to-node=\"14\" data-index-in-node=\"161\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"203\"\u003eConjugation:\u003c\/b\u003e Drug Affinity Complex (DAC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"244\"\u003eHalf-Life:\u003c\/b\u003e 6 to 8 Days (Long-Acting) \u003cb data-path-to-node=\"14\" data-index-in-node=\"281\"\u003ePurity:\u003c\/b\u003e \u0026gt;99% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"301\"\u003eContent:\u003c\/b\u003e Available in 5mg and 10mg vials\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eCJC-1295 with DAC\u003c\/b\u003e is a long-acting, tetrasubstituted analogue of Growth Hormone-Releasing Hormone (GHRH). It is distinguished by its unique \u003cb data-path-to-node=\"17\" data-index-in-node=\"140\"\u003eDrug Affinity Complex (DAC)\u003c\/b\u003e technology, which conjugates the peptide to serum albumin in vivo.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eThis conjugation extends the biological half-life from minutes to \u003cb data-path-to-node=\"18\" data-index-in-node=\"66\"\u003e6–8 days\u003c\/b\u003e, creating a sustained elevation of Growth Hormone (GH) and IGF-1. This contrasts with \"Modified GRF 1-29\" (No DAC), which produces short, pulsatile spikes. This formulation is the primary subject of research for protocols requiring once-weekly administration and steady-state hormone elevation.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: In Vivo Bioconjugation\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eCJC-1295 utilizes a sophisticated \"Trojan Horse\" delivery system via the DAC moiety.\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eMaleimide Linker:\u003c\/b\u003e The peptide contains a maleimide group at the C-terminus that reacts specifically with \u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"105\"\u003eCysteine-34\u003c\/b\u003e on circulating serum albumin.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eAlbumin Shielding:\u003c\/b\u003e Once bound to albumin (67 kDa), the peptide is shielded from enzymatic degradation (DPP-IV) and is too large to be filtered by the kidneys.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eSustained Release:\u003c\/b\u003e The albumin conjugate circulates for weeks, providing continuous stimulation to the pituitary GHRH receptors.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Sustained GH \u0026amp; IGF-1 Elevation\u003c\/b\u003e Clinical research (Teichman et al.) demonstrated that a single injection increases mean GH levels by \u003cb data-path-to-node=\"25\" data-index-in-node=\"135\"\u003e2- to 10-fold\u003c\/b\u003e and sustains elevated IGF-1 for up to \u003cb data-path-to-node=\"25\" data-index-in-node=\"187\"\u003e28 days\u003c\/b\u003e. This makes it ideal for research into chronic anabolism and lipolysis where daily injections are not feasible.\u003c\/p\u003e\n\u003cp data-path-to-node=\"26\"\u003e\u003cb data-path-to-node=\"26\" data-index-in-node=\"0\"\u003e2. GHRH Knockout Rescue\u003c\/b\u003e In GHRH knockout models, once-weekly administration of CJC-1295 was sufficient to normalize growth and induce pituitary hyperplasia (growth of somatotroph cells), proving its potent trophic effects.\u003c\/p\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e3. Lipodystrophy \u0026amp; Metabolic Research\u003c\/b\u003e Investigated for its ability to redistribute visceral fat and improve metabolic profiles in lipodystrophy models. The continuous GH pressure drives profound lipolysis via Hormone Sensitive Lipase (HSL).\u003c\/p\u003e\n\u003chr data-path-to-node=\"28\"\u003e\n\u003ch3 data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003eImportant Distinction: DAC vs. No DAC\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003eCJC-1295 with DAC:\u003c\/b\u003e Half-life of \u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"32\"\u003e6-8 days\u003c\/b\u003e. Causes a \"bleed\" or continuous wave of GH. Dosed weekly.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003eModified GRF 1-29 (No DAC):\u003c\/b\u003e Half-life of \u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"41\"\u003e30 minutes\u003c\/b\u003e. Causes distinct pulses. Dosed 3x daily.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,0\"\u003e\u003ci data-path-to-node=\"30,2,0\" data-index-in-node=\"0\"\u003eThis listing is for the DAC (Long-Acting) variant.\u003c\/i\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"33\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,0,0\"\u003e\u003cb data-path-to-node=\"33,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,1,0\"\u003e\u003cb data-path-to-node=\"33,1,0\" data-index-in-node=\"0\"\u003eStorage (Lyophilized):\u003c\/b\u003e Store at -20°C (Freezer). Stable for \u0026gt;24 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,0\"\u003e\u003cb data-path-to-node=\"33,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"33,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,0,0\"\u003e\u003cb data-path-to-node=\"33,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Bacteriostatic Water or Sterile Saline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,1,0\"\u003e\u003cb data-path-to-node=\"33,2,1,1,0\" data-index-in-node=\"0\"\u003eSolubility:\u003c\/b\u003e Highly soluble.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,3,0\"\u003e\u003cb data-path-to-node=\"33,3,0\" data-index-in-node=\"0\"\u003eStorage (Reconstituted):\u003c\/b\u003e Store at 4°C (Refrigerator). While more stable than native GHRH, use within 14-21 days to ensure the maleimide linker remains active for conjugation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"34\"\u003e\n\u003ch3 data-path-to-node=\"35\"\u003e\u003cb data-path-to-node=\"35\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"36\"\u003e\u003cb data-path-to-node=\"36\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47710005002454,"sku":"CJC-DAC-10","price":63.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/CJC-1295-With-DAC-10mg.png?v=1768509489"},{"product_id":"follistatin-344-fs344-myostatin-research-protein","title":"Follistatin 344 Research Protein – 1mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eFollistatin 344 (FS344) Peptide\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eIsoform:\u003c\/b\u003e Follistatin-315 (FS315) - Systemic Isoform \u003cb data-path-to-node=\"14\" data-index-in-node=\"52\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"94\"\u003eMechanism:\u003c\/b\u003e High-Affinity Ligand Trap (TGF-β Superfamily) \u003cb data-path-to-node=\"14\" data-index-in-node=\"151\"\u003ePurity:\u003c\/b\u003e \u0026gt;95% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"171\"\u003eContent:\u003c\/b\u003e 1mg per vial\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eFollistatin 344\u003c\/b\u003e is a recombinant glycoprotein designed to inhibit members of the TGF-β superfamily, most notably \u003cb data-path-to-node=\"17\" data-index-in-node=\"113\"\u003eMyostatin (GDF-8)\u003c\/b\u003e and \u003cb data-path-to-node=\"17\" data-index-in-node=\"135\"\u003eActivin A\u003c\/b\u003e. It corresponds to the alternatively spliced transcript that encodes the \u003cb data-path-to-node=\"17\" data-index-in-node=\"218\"\u003eFS315\u003c\/b\u003e isoform.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eUnlike the tissue-bound FS288 isoform, Follistatin 344 contains an acidic C-terminal tail that masks its heparin-binding site. This modification allows it to circulate freely in the bloodstream, making it the preferred reagent for research requiring systemic muscle hypertrophy and metabolic modulation.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The Ligand Trap\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eFollistatin 344 acts as a \"molecular clamp,\" physically sequestering ligands to prevent them from binding to their receptors (ActRIIB).\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eMyostatin Inhibition:\u003c\/b\u003e By neutralizing Myostatin, the primary negative regulator of muscle mass, Follistatin releases the \"brake\" on muscle growth, driving hypertrophy via the activation of mTOR and satellite cell fusion.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eActivin A Blockade:\u003c\/b\u003e Follistatin binds Activin A with even higher affinity than Myostatin. This is crucial for its anti-inflammatory effects and its ability to suppress fibrosis in models of muscular dystrophy.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eWnt Signaling:\u003c\/b\u003e In hair follicle research, it antagonizes BMPs to permit Wnt-mediated transition from the resting (telogen) to growth (anagen) phase.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Musculoskeletal Hypertrophy\u003c\/b\u003e Follistatin 344 is the gold standard for inducing rapid muscle growth.\u003c\/p\u003e\n\u003cul data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eHypertrophy:\u003c\/b\u003e Studies report gains of \u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"37\"\u003e20% to \u0026gt;100%\u003c\/b\u003e in muscle mass depending on the model (e.g., AAV gene therapy vs. peptide).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,1,0\"\u003e\u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"0\"\u003eFiber Type:\u003c\/b\u003e Drives a shift toward glycolytic (Type II) fibers, increasing force generation capacity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e2. Disease Models (Dystrophy \u0026amp; SMA)\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"28\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,0,0\"\u003e\u003cb data-path-to-node=\"28,0,0\" data-index-in-node=\"0\"\u003eSpinal Muscular Atrophy (SMA):\u003c\/b\u003e In murine models, daily administration extended lifespan by ~30% and increased motor neuron survival.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,1,0\"\u003e\u003cb data-path-to-node=\"28,1,0\" data-index-in-node=\"0\"\u003eDuchenne Muscular Dystrophy:\u003c\/b\u003e Unlike myostatin-specific antibodies, Follistatin also blocks Activin A, significantly reducing \u003cb data-path-to-node=\"28,1,0\" data-index-in-node=\"125\"\u003efibrosis\u003c\/b\u003e (scar tissue) in dystrophic muscle.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003e3. Inflammation \u0026amp; Metabolism\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003eCytokine Storm:\u003c\/b\u003e Acts as a potent anti-inflammatory by neutralizing the Activin A surge seen in sepsis and endotoxemia.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003eMetabolic Health:\u003c\/b\u003e Hypertrophied muscle acts as a glucose sink, improving insulin sensitivity and reducing visceral fat mass in obesity models.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"33\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,0,0\"\u003e\u003cb data-path-to-node=\"33,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,1,0\"\u003e\u003cb data-path-to-node=\"33,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 12 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,0\"\u003e\u003cb data-path-to-node=\"33,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"33,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,0,0\"\u003e\u003cb data-path-to-node=\"33,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Bacteriostatic Water or Sterile PBS (pH 7.4).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,1,0\"\u003e\u003cb data-path-to-node=\"33,2,1,1,0\" data-index-in-node=\"0\"\u003eCarrier Protein:\u003c\/b\u003e Recommended to add \u003cb data-path-to-node=\"33,2,1,1,0\" data-index-in-node=\"36\"\u003e0.1% BSA\u003c\/b\u003e or HSA to prevent adsorption to the vial wall.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,3,0\"\u003e\u003cb data-path-to-node=\"33,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C. \u003cb data-path-to-node=\"33,3,0\" data-index-in-node=\"32\"\u003eDo not freeze-thaw repeatedly.\u003c\/b\u003e Use aliquots.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"34\"\u003e\n\u003ch3 data-path-to-node=\"35\"\u003e\u003cb data-path-to-node=\"35\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"36\"\u003e\u003cb data-path-to-node=\"36\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47710043406550,"sku":"FOLL344-1","price":120.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/Follistatin-344-1mg.png?v=1768509451"},{"product_id":"ghrp-6-ghs-r1a-research-peptide","title":"GHRP-6 Research Peptide – 5mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eGHRP-6 Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 \u003cb data-path-to-node=\"14\" data-index-in-node=\"42\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"84\"\u003eClass:\u003c\/b\u003e Growth Hormone Secretagogue (GHS) \u003cb data-path-to-node=\"14\" data-index-in-node=\"125\"\u003ePurity:\u003c\/b\u003e \u0026gt;98% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"145\"\u003eContent:\u003c\/b\u003e 5mg per vial\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eGHRP-6\u003c\/b\u003e is a synthetic hexapeptide and the first true Growth Hormone Secretagogue (GHS) developed. It acts as a potent agonist of the \u003cb data-path-to-node=\"17\" data-index-in-node=\"133\"\u003eGhrelin Receptor (GHS-R1a)\u003c\/b\u003e, mimicking the hunger hormone ghrelin to stimulate the release of Growth Hormone (GH) from the pituitary gland.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eUnlike newer, selective secretagogues (like Ipamorelin), GHRP-6 retains a broad pharmacological profile. It is renowned for its intense \u003cb data-path-to-node=\"18\" data-index-in-node=\"136\"\u003eorexigenic (appetite-stimulating)\u003c\/b\u003e effects and its secondary action on the \u003cb data-path-to-node=\"18\" data-index-in-node=\"210\"\u003eCD36 receptor\u003c\/b\u003e, which confers significant cytoprotective and anti-inflammatory properties in cardiac and gastric tissues.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The Dual-Pathway Agonist\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eGHRP-6 operates via distinct receptor interactions that drive both hormonal and survival signaling.\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eGHS-R1a Activation (GH Release):\u003c\/b\u003e Binds to receptors in the pituitary and hypothalamus, triggering the PLC-IP3 pathway. This causes a massive influx of calcium that releases stored Growth Hormone vesicles.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eCD36 Interaction (Cytoprotection):\u003c\/b\u003e Binds to the CD36 scavenger receptor on heart and endothelial cells. This activates the \u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"123\"\u003ePI3K\/Akt pathway\u003c\/b\u003e, increasing the Bcl-2\/Bax ratio to prevent apoptosis (cell death) during ischemic stress.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eHypothalamic Signaling:\u003c\/b\u003e Activates \u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"34\"\u003eNPY\/AgRP neurons\u003c\/b\u003e in the arcuate nucleus, driving a powerful hunger signal and metabolic shift toward anabolism.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Potent GH Secretion \u0026amp; Diagnostics\u003c\/b\u003e GHRP-6 is one of the most powerful GH releasers available.\u003c\/p\u003e\n\u003cul data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eDiagnostic Standard:\u003c\/b\u003e The combination of GHRH + GHRP-6 is the \"Gold Standard\" provocation test for diagnosing Adult GH Deficiency, capable of stimulating GH release even when other agents fail.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,1,0\"\u003e\u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"0\"\u003eSynergy:\u003c\/b\u003e Exhibits massive synergy when stacked with GHRH analogs (like CJC-1295), creating a GH pulse far greater than the sum of individual administrations.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e2. Appetite \u0026amp; Cachexia\u003c\/b\u003e Investigated for treating wasting conditions (cachexia).\u003c\/p\u003e\n\u003cul data-path-to-node=\"28\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,0,0\"\u003e\u003cb data-path-to-node=\"28,0,0\" data-index-in-node=\"0\"\u003eHyperphagia:\u003c\/b\u003e Induces rapid, intense hunger by mimicking ghrelin, making it a primary tool for reversing involuntary weight loss and anorexia in disease models.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003e3. Cardioprotection \u0026amp; Tissue Repair\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003eIschemia Reperfusion:\u003c\/b\u003e Reduces heart tissue damage following heart attacks by preventing mitochondrial collapse via the CD36 pathway.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003eGastric Protection:\u003c\/b\u003e Acts as a potent cytoprotectant in the stomach, preventing stress ulcers and accelerating gastric emptying (prokinetic effect) in models of diabetic gastroparesis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"33\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,0,0\"\u003e\u003cb data-path-to-node=\"33,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,1,0\"\u003e\u003cb data-path-to-node=\"33,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 36 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,0\"\u003e\u003cb data-path-to-node=\"33,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"33,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,0,0\"\u003e\u003cb data-path-to-node=\"33,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Bacteriostatic Water or Sterile Saline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,1,0\"\u003e\u003cb data-path-to-node=\"33,2,1,1,0\" data-index-in-node=\"0\"\u003eSolubility:\u003c\/b\u003e Highly soluble due to cationic residues.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,3,0\"\u003e\u003cb data-path-to-node=\"33,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C (Refrigerator). Use within 3-4 weeks.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"34\"\u003e\n\u003ch3 data-path-to-node=\"35\"\u003e\u003cb data-path-to-node=\"35\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"36\"\u003e\u003cb data-path-to-node=\"36\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47710089085142,"sku":"GHRP6-5","price":29.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/GHRP-6-5mg.png?v=1768509420"},{"product_id":"ghrp-2-pralmorelin-research-peptide","title":"GHRP-2 Research Peptide – 5mg \/ 10mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eGHRP-2 Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 \u003cb data-path-to-node=\"14\" data-index-in-node=\"46\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"88\"\u003eClass:\u003c\/b\u003e Growth Hormone Secretagogue (GHS) \u003cb data-path-to-node=\"14\" data-index-in-node=\"129\"\u003ePurity:\u003c\/b\u003e \u0026gt;98% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"149\"\u003eContent:\u003c\/b\u003e Available in 5mg and 10mg vials\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eGHRP-2 (Pralmorelin)\u003c\/b\u003e is a synthetic hexapeptide and a \"super-analog\" of GHRP-6. It is one of the most potent Growth Hormone Secretagogues (GHS) available, with an \u003cb data-path-to-node=\"17\" data-index-in-node=\"163\"\u003eED50 of 0.6 nmol\/kg\u003c\/b\u003e (significantly more potent than GHRP-6 or Ipamorelin).\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eUnlike selective agonists, GHRP-2 retains a promiscuous receptor profile similar to the endogenous hormone ghrelin. This results in broad physiological effects, including potent GH release, significant stimulation of the \u003cb data-path-to-node=\"18\" data-index-in-node=\"221\"\u003eHPA axis (Cortisol\/ACTH)\u003c\/b\u003e, and appetite stimulation. It is a critical reagent for researching conditions of growth failure, catabolic wasting, and hypothalamic dysfunction.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: Multi-Axis Stimulation\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eGHRP-2 operates via the \u003cb data-path-to-node=\"21\" data-index-in-node=\"24\"\u003ePLC-IP3-Calcium\u003c\/b\u003e pathway, distinct from GHRH's cAMP pathway.\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eGHS-R1a Activation:\u003c\/b\u003e Binds with high affinity to receptors in the pituitary and hypothalamus, triggering massive calcium influx and GH exocytosis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eHPA Axis Stimulation:\u003c\/b\u003e uniquely stimulates the release of \u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"57\"\u003eACTH\u003c\/b\u003e and \u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"66\"\u003eCortisol\u003c\/b\u003e, making it a valuable probe for adrenal insufficiency (GHRP-2 Test).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eSynergy:\u003c\/b\u003e When co-administered with GHRH, it produces a \u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"55\"\u003e54-fold increase\u003c\/b\u003e in GH secretion, far exceeding the sum of individual administrations.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,3,0\"\u003e\u003cb data-path-to-node=\"22,3,0\" data-index-in-node=\"0\"\u003eCD36 Interaction:\u003c\/b\u003e Activates the CD36 scavenger receptor, providing cardioprotection against ischemia-reperfusion injury via the RISK and SAFE kinase pathways.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Endocrine Diagnostics \u0026amp; Growth\u003c\/b\u003e GHRP-2 is the benchmark for provoking maximal GH release.\u003c\/p\u003e\n\u003cul data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eDiagnostic Utility:\u003c\/b\u003e Investigated as a single-agent test for both GH and ACTH deficiency, offering high specificity (100%) and sensitivity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,1,0\"\u003e\u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"0\"\u003eGrowth Rescue:\u003c\/b\u003e In genetic models (like \u003ci data-path-to-node=\"26,1,0\" data-index-in-node=\"39\"\u003elit\/lit\u003c\/i\u003e mice), it stimulates growth even in the absence of functional GHRH receptors.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e2. Catabolism \u0026amp; Appetite\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"28\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,0,0\"\u003e\u003cb data-path-to-node=\"28,0,0\" data-index-in-node=\"0\"\u003eOrexigenic Effect:\u003c\/b\u003e Increases food intake by ~36% in human trials by activating NPY\/AgRP neurons in the hypothalamus.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,1,0\"\u003e\u003cb data-path-to-node=\"28,1,0\" data-index-in-node=\"0\"\u003eAnti-Catabolic:\u003c\/b\u003e Prevents muscle wasting in inflammatory states (e.g., arthritis) by downregulating the ubiquitin ligases \u003cb data-path-to-node=\"28,1,0\" data-index-in-node=\"121\"\u003eMuRF1\u003c\/b\u003e and \u003cb data-path-to-node=\"28,1,0\" data-index-in-node=\"131\"\u003eMAFbx\u003c\/b\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003e3. Cardioprotection\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003eStunning Recovery:\u003c\/b\u003e Pretreatment with GHRP-2 fully protects heart muscle from diastolic dysfunction (stunning) following ischemia.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003eInfarct Reduction:\u003c\/b\u003e Research indicates it reduces myocardial infarct size by preventing mitochondrial permeability transition pore (mPTP) opening.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"33\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,0,0\"\u003e\u003cb data-path-to-node=\"33,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,1,0\"\u003e\u003cb data-path-to-node=\"33,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 24 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,0\"\u003e\u003cb data-path-to-node=\"33,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"33,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,0,0\"\u003e\u003cb data-path-to-node=\"33,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Bacteriostatic Water or Sterile Saline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,1,0\"\u003e\u003cb data-path-to-node=\"33,2,1,1,0\" data-index-in-node=\"0\"\u003eSolubility:\u003c\/b\u003e Highly soluble.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,3,0\"\u003e\u003cb data-path-to-node=\"33,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C (Refrigerator). Use within 7 days to prevent oxidation of the Tryptophan residue. \u003cb data-path-to-node=\"33,3,0\" data-index-in-node=\"113\"\u003eAvoid freeze-thaw cycles.\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"34\"\u003e\n\u003ch3 data-path-to-node=\"35\"\u003e\u003cb data-path-to-node=\"35\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"36\"\u003e\u003cb data-path-to-node=\"36\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"5mg","offer_id":47710089445590,"sku":"GHRP2-5","price":29.0,"currency_code":"USD","in_stock":true},{"title":"10mg","offer_id":47710089478358,"sku":"GHRP2-10","price":36.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/GHRP-2-5mg.png?v=1768509327"},{"product_id":"hexarelin-acetate-ghs-r1a-research-peptide","title":"Hexarelin Acetate Research Peptide – 5mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eHexarelin Acetate Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e His-D-2-MeTrp-Ala-Trp-D-Phe-Lys-NH2 \u003cb data-path-to-node=\"14\" data-index-in-node=\"46\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"88\"\u003eClass:\u003c\/b\u003e Growth Hormone Secretagogue (GHS) \u003cb data-path-to-node=\"14\" data-index-in-node=\"129\"\u003ePurity:\u003c\/b\u003e \u0026gt;99% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"149\"\u003eContent:\u003c\/b\u003e 5mg per vial\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eHexarelin\u003c\/b\u003e is a synthetic hexapeptide and a \"super-agonist\" of the Growth Hormone Secretagogue Receptor (GHS-R1a). It is chemically modified with D-amino acids (D-2-Methyl-Trp, D-Phe) to resist enzymatic degradation, giving it a prolonged half-life and potency superior to native ghrelin.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eUnlike selective secretagogues, Hexarelin exhibits a unique dual-receptor pharmacology. It activates both the \u003cb data-path-to-node=\"18\" data-index-in-node=\"110\"\u003eGHS-R1a\u003c\/b\u003e (endocrine axis) and the \u003cb data-path-to-node=\"18\" data-index-in-node=\"143\"\u003eCD36 Scavenger Receptor\u003c\/b\u003e (cardiovascular\/metabolic axis). This pleiotropic profile makes it a critical reagent for researching cardiac ischemia, neuroprotection, and metabolic regulation.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The Dual-Receptor Agonist\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eHexarelin operates via two distinct signaling pathways:\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eGHS-R1a Activation (Endocrine):\u003c\/b\u003e Binds to pituitary receptors with high affinity, triggering the PLC-IP3 pathway and massive calcium influx. This releases a \"reserve pool\" of Growth Hormone vesicles, creating a pulse larger than GHRH alone.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eCD36 Interaction (Cardio-Metabolic):\u003c\/b\u003e Binds to the CD36 receptor on heart and immune cells. This activates \u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"106\"\u003ePPAR-gamma\u003c\/b\u003e and the \u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"125\"\u003ePI3K\/Akt pathway\u003c\/b\u003e, promoting cell survival, mitochondrial biogenesis, and cholesterol efflux from macrophages.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Potent GH Secretion\u003c\/b\u003e Hexarelin is one of the most powerful GH releasers known.\u003c\/p\u003e\n\u003cul data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eSuper-Agonist:\u003c\/b\u003e Capable of stimulating GH release even in models of somatostatin inhibition.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,1,0\"\u003e\u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"0\"\u003eMetabolic Rescue:\u003c\/b\u003e In diabetic models, it restores GH pulsatility (though IGF-1 response depends on insulin status).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e2. Cardioprotection \u0026amp; Ischemia\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"28\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,0,0\"\u003e\u003cb data-path-to-node=\"28,0,0\" data-index-in-node=\"0\"\u003eInotropy:\u003c\/b\u003e Increases cardiac contractility (squeeze) without significantly raising heart rate, improving ejection fraction in ischemic models.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,1,0\"\u003e\u003cb data-path-to-node=\"28,1,0\" data-index-in-node=\"0\"\u003eInfarct Reduction:\u003c\/b\u003e Pretreatment significantly reduces the size of necrotic tissue following heart attacks (ischemia-reperfusion injury).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003e3. Neuroprotection\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003eSurvival Kinases:\u003c\/b\u003e Protects neurons from oxidative stress and toxicity (e.g., chemotherapy) by activating the PI3K\/Akt survival pathway and inhibiting caspase-3 (apoptosis).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"31\"\u003e\u003cb data-path-to-node=\"31\" data-index-in-node=\"0\"\u003e4. Metabolic Regulation\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"32\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"32,0,0\"\u003e\u003cb data-path-to-node=\"32,0,0\" data-index-in-node=\"0\"\u003eLipid Metabolism:\u003c\/b\u003e Promotes the clearance of triglycerides and cholesterol via CD36\/PPAR-gamma signaling in the liver and macrophages.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"33\"\u003e\n\u003ch3 data-path-to-node=\"34\"\u003e\u003cb data-path-to-node=\"34\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"35\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"35,0,0\"\u003e\u003cb data-path-to-node=\"35,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"35,1,0\"\u003e\u003cb data-path-to-node=\"35,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 36 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"35,2,0\"\u003e\u003cb data-path-to-node=\"35,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"35,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"35,2,1,0,0\"\u003e\u003cb data-path-to-node=\"35,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Bacteriostatic Water or Sterile Saline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"35,2,1,1,0\"\u003e\u003cb data-path-to-node=\"35,2,1,1,0\" data-index-in-node=\"0\"\u003eSolubility:\u003c\/b\u003e Highly soluble.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"35,3,0\"\u003e\u003cb data-path-to-node=\"35,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C (Refrigerator). Use within 14-21 days. \u003cb data-path-to-node=\"35,3,0\" data-index-in-node=\"70\"\u003eAvoid freeze-thaw cycles.\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"36\"\u003e\n\u003ch3 data-path-to-node=\"37\"\u003e\u003cb data-path-to-node=\"37\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"38\"\u003e\u003cb data-path-to-node=\"38\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47712186990806,"sku":"HEXAR-5","price":36.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/Hexarelin-5mg_bb7d043e-4e91-42ae-9b53-80008e2bb244.png?v=1768510031"},{"product_id":"igf-1-lr3-long-r3-igf-1-research-peptide","title":"IGF-1 LR3 Research Peptide – 1mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eIGF-1 LR3 Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e Modified Human IGF-1 (83 Amino Acids) \u003cb data-path-to-node=\"14\" data-index-in-node=\"48\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"90\"\u003eModifications:\u003c\/b\u003e Glu3→Arg3 Substitution + 13 AA N-Terminal Extension \u003cb data-path-to-node=\"14\" data-index-in-node=\"157\"\u003ePurity:\u003c\/b\u003e \u0026gt;95% (SDS-PAGE \/ Receptor Grade) \u003cb data-path-to-node=\"14\" data-index-in-node=\"198\"\u003eContent:\u003c\/b\u003e 1mg per vial\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eIGF-1 LR3 (Long R3 Insulin-like Growth Factor-1)\u003c\/b\u003e is a recombinant analog of human IGF-1, engineered to overcome the pharmacokinetic limitations of the native hormone.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eWhile native IGF-1 has a half-life of minutes and is tightly sequestered by binding proteins (IGFBPs), IGF-1 LR3 incorporates two critical modifications:\u003c\/p\u003e\n\u003col start=\"1\" data-path-to-node=\"19\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"19,0,0\"\u003e\u003cb data-path-to-node=\"19,0,0\" data-index-in-node=\"0\"\u003eArg3 Substitution:\u003c\/b\u003e Prevents binding to IGFBPs, keeping the peptide \"free\" and bioactive.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"19,1,0\"\u003e\u003cb data-path-to-node=\"19,1,0\" data-index-in-node=\"0\"\u003eN-Terminal Extension:\u003c\/b\u003e Increases metabolic stability and half-life to \u003cb data-path-to-node=\"19,1,0\" data-index-in-node=\"69\"\u003e20-30 hours\u003c\/b\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp data-path-to-node=\"20\"\u003eThis design creates a molecule that is \u003cb data-path-to-node=\"20\" data-index-in-node=\"39\"\u003e2-3 times more potent\u003c\/b\u003e than native IGF-1 in driving anabolism and nitrogen retention in research models.\u003c\/p\u003e\n\u003chr data-path-to-node=\"21\"\u003e\n\u003ch3 data-path-to-node=\"22\"\u003e\u003cb data-path-to-node=\"22\" data-index-in-node=\"0\"\u003eMechanism of Action: The Unbound Agonist\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"23\"\u003eIGF-1 LR3 bypasses the body's natural regulatory buffers to deliver sustained signaling.\u003c\/p\u003e\n\u003cul data-path-to-node=\"24\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"24,0,0\"\u003e\u003cb data-path-to-node=\"24,0,0\" data-index-in-node=\"0\"\u003ePI3K\/Akt\/mTOR Pathway:\u003c\/b\u003e Activates the primary engine of protein synthesis. It recruits IRS-1 and PI3K, leading to the phosphorylation of mTOR, which drives ribosomal activity and muscle hypertrophy.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"24,1,0\"\u003e\u003cb data-path-to-node=\"24,1,0\" data-index-in-node=\"0\"\u003eFoxO Suppression:\u003c\/b\u003e Phosphorylates FoxO transcription factors, trapping them in the cytoplasm. This prevents them from transcribing muscle atrophy genes (\u003cb data-path-to-node=\"24,1,0\" data-index-in-node=\"152\"\u003eAtrogin-1\u003c\/b\u003e, \u003cb data-path-to-node=\"24,1,0\" data-index-in-node=\"163\"\u003eMuRF1\u003c\/b\u003e), effectively blocking protein breakdown.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"24,2,0\"\u003e\u003cb data-path-to-node=\"24,2,0\" data-index-in-node=\"0\"\u003eGlucose Partitioning:\u003c\/b\u003e Cross-activates Insulin\/IGF-1 Hybrid Receptors on muscle cells, driving GLUT4 translocation and glucose uptake independently of insulin levels.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"25\"\u003e\n\u003ch3 data-path-to-node=\"26\"\u003e\u003cb data-path-to-node=\"26\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e1. Musculoskeletal Hypertrophy\u003c\/b\u003e IGF-1 LR3 is the gold standard for research into rapid muscle growth.\u003c\/p\u003e\n\u003cul data-path-to-node=\"28\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,0,0\"\u003e\u003cb data-path-to-node=\"28,0,0\" data-index-in-node=\"0\"\u003ePotency:\u003c\/b\u003e In nitrogen balance studies (Tomas et al.), LR3 was significantly more effective than native IGF-1 at promoting weight gain and nitrogen retention, even with once-daily dosing.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,1,0\"\u003e\u003cb data-path-to-node=\"28,1,0\" data-index-in-node=\"0\"\u003eDifferentiation:\u003c\/b\u003e Promotes both the proliferation of satellite cells (via MAPK) and their fusion into myotubes (via Myogenin), supporting hyperplasia and hypertrophy.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003e2. Metabolic Partitioning\u003c\/b\u003e Investigated for its \"leaning\" effect.\u003c\/p\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003eNutrient Shuttling:\u003c\/b\u003e Drives glucose and amino acids into muscle tissue while suppressing insulin secretion. Low insulin disinhibits lipolysis (fat breakdown), shifting the metabolic preference toward burning fat for fuel.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"31\"\u003e\u003cb data-path-to-node=\"31\" data-index-in-node=\"0\"\u003e3. Cell Culture \u0026amp; Bioengineering\u003c\/b\u003e Widely used in serum-free media to maintain \u003cb data-path-to-node=\"31\" data-index-in-node=\"77\"\u003estem cells (iPSCs\/hESCs)\u003c\/b\u003e. Its stability allows for less frequent media changes while maintaining pluripotency and survival better than native growth factors.\u003c\/p\u003e\n\u003chr data-path-to-node=\"32\"\u003e\n\u003ch3 data-path-to-node=\"33\"\u003e\u003cb data-path-to-node=\"33\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"34\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,0,0\"\u003e\u003cb data-path-to-node=\"34,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,1,0\"\u003e\u003cb data-path-to-node=\"34,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 12 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,2,0\"\u003e\u003cb data-path-to-node=\"34,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"34,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,2,1,0,0\"\u003e\u003cb data-path-to-node=\"34,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e \u003cb data-path-to-node=\"34,2,1,0,0\" data-index-in-node=\"9\"\u003e10-100mM HCl\u003c\/b\u003e or \u003cb data-path-to-node=\"34,2,1,0,0\" data-index-in-node=\"25\"\u003eAcetic Acid\u003c\/b\u003e is often recommended for the initial dissolution to prevent aggregation, followed by dilution with sterile buffer. Alternatively, use Bacteriostatic Water if using immediately.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,3,0\"\u003e\u003cb data-path-to-node=\"34,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C. \u003cb data-path-to-node=\"34,3,0\" data-index-in-node=\"32\"\u003eVery sensitive to degradation.\u003c\/b\u003e Use within 7 days. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"35\"\u003e\n\u003ch3 data-path-to-node=\"36\"\u003e\u003cb data-path-to-node=\"36\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"37\"\u003e\u003cb data-path-to-node=\"37\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47712189219030,"sku":"IGF1LR3-1","price":47.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/IGF-1LR3-1mg.png?v=1768509272"},{"product_id":"ipamorelin-ghs-r1a-research-peptide","title":"Ipamorelin Research Peptide – 10mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eIpamorelin Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e Aib-His-D-2-Nal-D-Phe-Lys-NH2 \u003cb data-path-to-node=\"14\" data-index-in-node=\"40\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"82\"\u003eClass:\u003c\/b\u003e Selective Growth Hormone Secretagogue (GHS) \u003cb data-path-to-node=\"14\" data-index-in-node=\"133\"\u003ePurity:\u003c\/b\u003e \u0026gt;98% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"153\"\u003eContent:\u003c\/b\u003e 5mg per vial\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eIpamorelin\u003c\/b\u003e is a third-generation synthetic pentapeptide and a highly selective agonist of the \u003cb data-path-to-node=\"17\" data-index-in-node=\"94\"\u003eGhrelin Receptor (GHS-R1a)\u003c\/b\u003e. It is distinguished from earlier secretagogues (like GHRP-6 and GHRP-2) by its \u003cb data-path-to-node=\"17\" data-index-in-node=\"201\"\u003eexquisite selectivity\u003c\/b\u003e.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eWhile promoting a potent pulsatile release of Growth Hormone (GH), Ipamorelin is unique in that it \u003cb data-path-to-node=\"18\" data-index-in-node=\"99\"\u003edoes not stimulate ACTH, Cortisol, or Prolactin\u003c\/b\u003e, even at high doses. This \"clean\" pharmacological profile makes it the preferred reagent for research requiring pure anabolic signaling without the \"endocrine noise\" of stress hormones.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The Selective Pulse\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eIpamorelin operates via the \u003cb data-path-to-node=\"21\" data-index-in-node=\"28\"\u003eGHS-R1a receptor\u003c\/b\u003e, initiating a cascade that mimics the body's natural growth hormone pulse.\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eSelective GHS-R1a Activation:\u003c\/b\u003e Binds to pituitary receptors, triggering the Gq\/11-PLC-IP3 pathway. This mobilizes intracellular calcium to release GH vesicles.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eNo Stress Hormone Spike:\u003c\/b\u003e Unlike GHRPs, it avoids cross-reactivity with receptors that trigger cortisol or prolactin, preventing catabolic side effects.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eAnabolic Signaling:\u003c\/b\u003e The released GH stimulates the liver to produce \u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"68\"\u003eIGF-1\u003c\/b\u003e, which activates the \u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"95\"\u003emTORC1 pathway\u003c\/b\u003e in muscle (protein synthesis) and the \u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"148\"\u003eRunx2 pathway\u003c\/b\u003e in bone (osteoblast differentiation).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Musculoskeletal Growth \u0026amp; Recovery\u003c\/b\u003e Ipamorelin is the gold standard for pure anabolic research.\u003c\/p\u003e\n\u003cul data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eHypertrophy:\u003c\/b\u003e Drives muscle protein synthesis via mTOR activation without cortisol-induced muscle wasting.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,1,0\"\u003e\u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"0\"\u003eBone Density:\u003c\/b\u003e Studies (Johansen et al.) show it increases Longitudinal Bone Growth Rate (LGR) and bone mineral content by stimulating osteoblasts, even counteracting glucocorticoid-induced bone loss.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e2. Metabolic Regulation \u0026amp; Body Composition\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"28\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,0,0\"\u003e\u003cb data-path-to-node=\"28,0,0\" data-index-in-node=\"0\"\u003eLipolysis:\u003c\/b\u003e Promotes fat loss by increasing metabolic rate and fatty acid oxidation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,1,0\"\u003e\u003cb data-path-to-node=\"28,1,0\" data-index-in-node=\"0\"\u003eNitrogen Balance:\u003c\/b\u003e Improves whole-body nitrogen retention by downregulating urea cycle enzymes in the liver, preserving amino acids for tissue repair.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003e3. Gastrointestinal Motility\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003ePostoperative Ileus:\u003c\/b\u003e Accelerates gastric emptying and reverses bowel paralysis (ileus) following surgery via cholinergic pathways in the gut, aiding recovery.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"33\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,0,0\"\u003e\u003cb data-path-to-node=\"33,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,1,0\"\u003e\u003cb data-path-to-node=\"33,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 36 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,0\"\u003e\u003cb data-path-to-node=\"33,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"33,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,0,0\"\u003e\u003cb data-path-to-node=\"33,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Bacteriostatic Water or Sterile Saline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,1,0\"\u003e\u003cb data-path-to-node=\"33,2,1,1,0\" data-index-in-node=\"0\"\u003eSolubility:\u003c\/b\u003e Highly soluble.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,3,0\"\u003e\u003cb data-path-to-node=\"33,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C (Refrigerator).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"34\"\u003e\n\u003ch3 data-path-to-node=\"35\"\u003e\u003cb data-path-to-node=\"35\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"36\"\u003e\u003cb data-path-to-node=\"36\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47712309870806,"sku":"IPAMOR-10","price":31.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/Ipamorelin-10mg.png?v=1768509242"},{"product_id":"mgf-mechano-growth-factor-igf-1ec-research-peptide","title":"MGF Research Peptide – 5mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eMGF Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys \u003cb data-path-to-node=\"14\" data-index-in-node=\"106\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"148\"\u003eIsoform:\u003c\/b\u003e IGF-1Ec C-Terminal Peptide \u003cb data-path-to-node=\"14\" data-index-in-node=\"184\"\u003ePurity:\u003c\/b\u003e \u0026gt;98% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"204\"\u003eContent:\u003c\/b\u003e 5mg per vial\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eMGF (Mechano Growth Factor)\u003c\/b\u003e is a splice variant of the IGF-1 gene (IGF-1Ec), naturally expressed in muscle tissue in response to mechanical stress and damage.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eUnlike systemic IGF-1 which drives differentiation, MGF acts as a local \u003cb data-path-to-node=\"18\" data-index-in-node=\"72\"\u003estem cell activator\u003c\/b\u003e. It triggers the proliferation of quiescent satellite cells (muscle stem cells), expanding the pool of myoblasts available for repair. It is a critical research tool for investigating the initial phase of muscle regeneration, neuroprotection, and cardiac repair.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The \"Activation\" Signal\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eMGF operates via a unique signaling pathway distinct from the IGF-1 receptor.\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eSatellite Cell Activation:\u003c\/b\u003e MGF drives quiescent satellite cells into the cell cycle (G0 -\u0026gt; G1), promoting rapid proliferation via the \u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"134\"\u003eMAPK\/ERK pathway\u003c\/b\u003e. This expands the \"raw material\" needed for tissue repair before differentiation begins.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eNeuroprotection:\u003c\/b\u003e Protects motor neurons and hippocampal neurons from ischemia and degeneration by stabilizing mitochondrial function and inhibiting caspase-3.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eCardioprotection:\u003c\/b\u003e Reduces cardiomyocyte apoptosis and recruits cardiac progenitor cells to sites of infarction (heart attack).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Musculoskeletal Regeneration\u003c\/b\u003e MGF is the primary signal for muscle repair.\u003c\/p\u003e\n\u003cul data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eHyperplasia:\u003c\/b\u003e Promotes the division of muscle cells (hyperplasia) rather than just size increase (hypertrophy).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,1,0\"\u003e\u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"0\"\u003eSarcopenia:\u003c\/b\u003e Research suggests that the age-related loss of muscle is due to a failure to express MGF; exogenous MGF can restore the proliferative capacity of aged muscle stem cells.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e2. Neurodegenerative Disease (ALS)\u003c\/b\u003e In mouse models of ALS (SOD1), MGF gene therapy significantly improved motor neuron survival compared to IGF-1, protecting neurons from \"suicide transport\" mechanisms.\u003c\/p\u003e\n\u003cp data-path-to-node=\"28\"\u003e\u003cb data-path-to-node=\"28\" data-index-in-node=\"0\"\u003e3. Ischemia \u0026amp; Stroke\u003c\/b\u003e Investigated for its ability to rescue neurons from delayed death following stroke. In gerbil models of brain ischemia, MGF treatment resulted in \u003cb data-path-to-node=\"28\" data-index-in-node=\"167\"\u003e74.5% survival\u003c\/b\u003e of vulnerable hippocampal neurons compared to near-total loss in controls.\u003c\/p\u003e\n\u003chr data-path-to-node=\"29\"\u003e\n\u003ch3 data-path-to-node=\"30\"\u003e\u003cb data-path-to-node=\"30\" data-index-in-node=\"0\"\u003eImportant Note: MGF vs. PEG-MGF\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"31\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"31,0,0\"\u003e\u003cb data-path-to-node=\"31,0,0\" data-index-in-node=\"0\"\u003eMGF (This Product):\u003c\/b\u003e Native sequence. Short half-life (~5-30 mins). Ideal for local administration mimicking the body's acute stress response.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"31,1,0\"\u003e\u003cb data-path-to-node=\"31,1,0\" data-index-in-node=\"0\"\u003ePEG-MGF:\u003c\/b\u003e PEGylated variant. Long half-life (days). Systemic distribution.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"31,2,0\"\u003e\u003ci data-path-to-node=\"31,2,0\" data-index-in-node=\"0\"\u003eThis listing is for the Native MGF peptide.\u003c\/i\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"32\"\u003e\n\u003ch3 data-path-to-node=\"33\"\u003e\u003cb data-path-to-node=\"33\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"34\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,0,0\"\u003e\u003cb data-path-to-node=\"34,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,1,0\"\u003e\u003cb data-path-to-node=\"34,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 12 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,2,0\"\u003e\u003cb data-path-to-node=\"34,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"34,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,2,1,0,0\"\u003e\u003cb data-path-to-node=\"34,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e \u003cb data-path-to-node=\"34,2,1,0,0\" data-index-in-node=\"9\"\u003eSterile 0.1% Acetic Acid\u003c\/b\u003e is recommended to ensure full dissolution of basic residues, followed by dilution with sterile water or saline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,2,1,1,0\"\u003e\u003cb data-path-to-node=\"34,2,1,1,0\" data-index-in-node=\"0\"\u003eStability:\u003c\/b\u003e Highly unstable once reconstituted. Use immediately or freeze single-use aliquots.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"34,3,0\"\u003e\u003cb data-path-to-node=\"34,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C. \u003cb data-path-to-node=\"34,3,0\" data-index-in-node=\"32\"\u003eDo not freeze-thaw repeatedly.\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"35\"\u003e\n\u003ch3 data-path-to-node=\"36\"\u003e\u003cb data-path-to-node=\"36\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"37\"\u003e\u003cb data-path-to-node=\"37\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47712362528982,"sku":"MGF-5","price":73.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/MGF-_IGF-1Ec_-5mg.png?v=1768509217"},{"product_id":"slu-pp-332-err-pan-agonist-research-tablets","title":"SLU-PP-332 Research Tablets – 250mcg \/ 1mg \/ 200mg – 60 Count","description":"\u003ch4 data-path-to-node=\"11\"\u003e\u003cstrong\u003eSLU-PP-332: The Mitochondrial Exercise Mimetic\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"12\"\u003e\u003cb data-path-to-node=\"12\" data-index-in-node=\"0\"\u003eChemical Name:\u003c\/b\u003e (E)-4-hydroxy-N'-(naphthalen-2-ylmethylene)benzohydrazide \u003cb data-path-to-node=\"12\" data-index-in-node=\"73\"\u003eFormat:\u003c\/b\u003e Oral Tablets \u003cb data-path-to-node=\"12\" data-index-in-node=\"94\"\u003eClass:\u003c\/b\u003e Estrogen-Related Receptor (ERR) Pan-Agonist \u003cb data-path-to-node=\"12\" data-index-in-node=\"145\"\u003ePurity:\u003c\/b\u003e ≥98% (HPLC) \u003cb data-path-to-node=\"12\" data-index-in-node=\"165\"\u003eTarget:\u003c\/b\u003e ERRα, ERRβ, and ERRγ Transcriptional Networks\u003c\/p\u003e\n\u003chr data-path-to-node=\"13\"\u003e\n\u003ch3 data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"15\"\u003e\u003cb data-path-to-node=\"15\" data-index-in-node=\"0\"\u003eSLU-PP-332\u003c\/b\u003e is a first-in-class small molecule designed to function as an \"exercise mimetic.\" Developed through a collaboration between Saint Louis University and Washington University, it acts as a potent pan-agonist of the \u003cb data-path-to-node=\"15\" data-index-in-node=\"224\"\u003eEstrogen-Related Receptor (ERR)\u003c\/b\u003e family.\u003c\/p\u003e\n\u003cp data-path-to-node=\"16\"\u003eUnlike standard weight-loss agents that target appetite, SLU-PP-332 operates directly on peripheral tissues. It induces a high-oxidative state in skeletal muscle, effectively \"tricking\" the body into simulating the systemic benefits of endurance training. It is a premier tool for researching the reversal of metabolic syndrome, obesity, and age-related physiological decline through direct transcriptional modulation.\u003c\/p\u003e\n\u003chr data-path-to-node=\"17\"\u003e\n\u003ch3 data-path-to-node=\"18\"\u003e\u003cb data-path-to-node=\"18\" data-index-in-node=\"0\"\u003eMechanism of Action: Transcriptional Fat Burning\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"19\"\u003eSLU-PP-332 bypasses mechanical work to activate the genetic programs associated with physical exertion.\u003c\/p\u003e\n\u003cul data-path-to-node=\"20\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"20,0,0\"\u003e\u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"0\"\u003eERR Activation:\u003c\/b\u003e Specifically targets \u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"37\"\u003eERRα\u003c\/b\u003e, the master regulator of mitochondrial biogenesis. It stabilizes the active conformation of the receptor, allowing for the recruitment of the co-activator \u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"197\"\u003ePGC-1α\u003c\/b\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"20,1,0\"\u003e\u003cb data-path-to-node=\"20,1,0\" data-index-in-node=\"0\"\u003eMitochondrial Overdrive:\u003c\/b\u003e Upregulates the \u003cb data-path-to-node=\"20,1,0\" data-index-in-node=\"41\"\u003ePdk4\u003c\/b\u003e gene, which switches cellular fuel preference from glucose to fatty acids. This results in a \u003cb data-path-to-node=\"20,1,0\" data-index-in-node=\"139\"\u003e2.5x increase in mitochondrial DNA\u003c\/b\u003e and enhanced ATP production within myocytes.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"20,2,0\"\u003e\u003cb data-path-to-node=\"20,2,0\" data-index-in-node=\"0\"\u003eTissue Remodeling:\u003c\/b\u003e Promotes the development of \u003cb data-path-to-node=\"20,2,0\" data-index-in-node=\"47\"\u003eType IIa oxidative muscle fibers\u003c\/b\u003e, which are highly resistant to fatigue.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"20,3,0\"\u003e\u003cb data-path-to-node=\"20,3,0\" data-index-in-node=\"0\"\u003eSTING Pathway Inhibition:\u003c\/b\u003e In aging models, it has been shown to shutdown the \u003cb data-path-to-node=\"20,3,0\" data-index-in-node=\"77\"\u003ecGAS-STING\u003c\/b\u003e inflammatory response, protecting vital organs like the kidneys from age-related decline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"21\"\u003e\n\u003ch3 data-path-to-node=\"22\"\u003e\u003cb data-path-to-node=\"22\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"23\"\u003e\u003cb data-path-to-node=\"23\" data-index-in-node=\"0\"\u003e1. Endurance \u0026amp; Physical Performance\u003c\/b\u003e Investigated for its ability to dramatically enhance aerobic capacity. In animal models, subjects treated with SLU-PP-332 were able to run \u003cb data-path-to-node=\"23\" data-index-in-node=\"175\"\u003e70% longer and 45% further\u003c\/b\u003e on treadmill tests compared to controls, despite no increase in actual physical activity.\u003c\/p\u003e\n\u003cp data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003e2. Obesity \u0026amp; Metabolic Syndrome\u003c\/b\u003e Research in Diet-Induced Obesity (DIO) models shows a \u003cb data-path-to-node=\"24\" data-index-in-node=\"86\"\u003e12% reduction in total body weight\u003c\/b\u003e and a 10-fold reduction in fat accumulation. The weight loss is driven by a ~25% increase in whole-body fat oxidation and resting energy expenditure.\u003c\/p\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e3. Geroprotection (Kidney \u0026amp; Muscle)\u003c\/b\u003e Studies in aged mice demonstrate that SLU-PP-332 reverses podocyte loss in the kidney and reduces albuminuria. It also promotes human myotube formation and fiber diameter, offering a model for treating \u003cb data-path-to-node=\"25\" data-index-in-node=\"238\"\u003esarcopenia\u003c\/b\u003e and muscle atrophy.\u003c\/p\u003e\n\u003cp data-path-to-node=\"26\"\u003e\u003cb data-path-to-node=\"26\" data-index-in-node=\"0\"\u003e4. Cardiovascular Support\u003c\/b\u003e Investigated for its ability to improve ejection fraction and survival rates in models of heart failure by normalizing oxidative phosphorylation profiles without inducing pathological hypertrophy.\u003c\/p\u003e\n\u003chr data-path-to-node=\"27\"\u003e\n\u003ch3 data-path-to-node=\"28\"\u003e\u003cb data-path-to-node=\"28\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"29\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"29,0,0\"\u003e\u003cb data-path-to-node=\"29,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Standardized oral tablets for precise experimental protocols.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"29,1,0\"\u003e\u003cb data-path-to-node=\"29,1,0\" data-index-in-node=\"0\"\u003eStorage:\u003c\/b\u003e Store in a cool, dry place away from direct light.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"29,2,0\"\u003e\u003cb data-path-to-node=\"29,2,0\" data-index-in-node=\"0\"\u003eLong-Term Storage:\u003c\/b\u003e Store at -20°C (Freezer) to maintain stability for up to 4 years.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"29,3,0\"\u003e\u003cb data-path-to-node=\"29,3,0\" data-index-in-node=\"0\"\u003eStability:\u003c\/b\u003e Highly stable in tablet form; the lyophilized powder is resistant to degradation at room temperature for up to 3 weeks during transit.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"30\"\u003e\n\u003ch3 data-path-to-node=\"31\"\u003e\u003cb data-path-to-node=\"31\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"250mcg","offer_id":47712730317014,"sku":"SLU-250x60","price":47.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":47712730349782,"sku":"SLU-1x60","price":70.0,"currency_code":"USD","in_stock":true},{"title":"200mg","offer_id":48153996853462,"sku":"SLU-200x60","price":758.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/SLU-PP-332-_250mcg_-x-60-Tablets.png?v=1768837142"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/collections\/Cellular_Energy_Pathway_Research_Collection.png?v=1781104256","url":"https:\/\/peptagon.com\/collections\/cellular-energy-pathway-research.oembed","provider":"Peptagon","version":"1.0","type":"link"}