{"product_id":"cjc-1295-no-dac-ipamorelin-cjc-ipa","title":"CJC-1295 No DAC + Ipamorelin Research Peptide Blend – 5mg \/ 5mg and 10mg \/ 10mg","description":"\u003ch4 data-path-to-node=\"4\"\u003e\u003cstrong\u003eCJC-1295 No DAC \u0026amp; Ipamorelin Blend (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"5\"\u003e\u003cb data-path-to-node=\"5\" data-index-in-node=\"0\"\u003eSequence (CJC-1295 No DAC):\u003c\/b\u003e Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 \u003cb data-path-to-node=\"5\" data-index-in-node=\"150\"\u003eSequence (Ipamorelin):\u003c\/b\u003e Aib-His-D-2-Nal-D-Phe-Lys-NH2 \u003cb data-path-to-node=\"5\" data-index-in-node=\"203\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"5\" data-index-in-node=\"245\"\u003ePurity:\u003c\/b\u003e \u0026gt;99% (HPLC)\u003cbr\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"9\"\u003eThis premium lyophilized blend combines \u003cb data-path-to-node=\"9\" data-index-in-node=\"40\"\u003eCJC-1295 No DAC\u003c\/b\u003e (Modified GRF 1-29) and \u003cb data-path-to-node=\"9\" data-index-in-node=\"80\"\u003eIpamorelin\u003c\/b\u003e to create a synergistic research tool for the investigation of the Growth Hormone (GH) axis.\u003c\/p\u003e\n\u003cp data-path-to-node=\"10\"\u003eUnlike recombinant hGH, which bypasses the pituitary, this blend utilizes \u003cb data-path-to-node=\"10\" data-index-in-node=\"74\"\u003e\"Neuroendocrine Synergy\"\u003c\/b\u003e to amplify the body’s natural, pulsatile GH secretion. It pairs a chemically stabilized Growth Hormone-Releasing Hormone (GHRH) analog with a highly selective Growth Hormone Secretagogue (GHS) to maximize signal efficiency without significant impact on cortisol or prolactin levels.\u003c\/p\u003e\n\u003chr data-path-to-node=\"11\"\u003e\n\u003ch3 data-path-to-node=\"12\"\u003e\u003cb data-path-to-node=\"12\" data-index-in-node=\"0\"\u003eMechanism of Action: The Power of Synergy\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"13\"\u003eThe efficacy of this co-formulation relies on targeting two distinct receptors simultaneously. Research suggests that the combined effect is greater than the sum of its parts (1+1 \u0026gt; 2).\u003c\/p\u003e\n\u003ch4 data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003e1. CJC-1295 No DAC (The Amplifier)\u003c\/b\u003e\u003c\/h4\u003e\n\u003cul data-path-to-node=\"15\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"15,0,0\"\u003e\u003cb data-path-to-node=\"15,0,0\" data-index-in-node=\"0\"\u003eClass:\u003c\/b\u003e GHRH Analog (Tetrasubstituted)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"15,1,0\"\u003e\u003cb data-path-to-node=\"15,1,0\" data-index-in-node=\"0\"\u003eMechanism:\u003c\/b\u003e Binds to the GHRH receptor on the anterior pituitary.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"15,2,0\"\u003e\u003cb data-path-to-node=\"15,2,0\" data-index-in-node=\"0\"\u003eAction:\u003c\/b\u003e Stimulates the \u003cb data-path-to-node=\"15,2,0\" data-index-in-node=\"23\"\u003esynthesis\u003c\/b\u003e of growth hormone by increasing intracellular cAMP. It effectively increases the \"pool\" of GH available for release.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"15,3,0\"\u003e\u003cb data-path-to-node=\"15,3,0\" data-index-in-node=\"0\"\u003eEngineering:\u003c\/b\u003e This \"No DAC\" variant features four specific amino acid substitutions (Tetrasubstitution) that protect it from DPP-IV enzymatic cleavage, extending its biological activity to 30-60 minutes—ideal for mimicking natural physiological pulses.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003e2. Ipamorelin (The Trigger)\u003c\/b\u003e\u003c\/h4\u003e\n\u003cul data-path-to-node=\"17\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,0,0\"\u003e\u003cb data-path-to-node=\"17,0,0\" data-index-in-node=\"0\"\u003eClass:\u003c\/b\u003e Selective GH Secretagogue (GHS)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,1,0\"\u003e\u003cb data-path-to-node=\"17,1,0\" data-index-in-node=\"0\"\u003eMechanism:\u003c\/b\u003e Binds to the Ghrelin receptor (GHS-R1a).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,2,0\"\u003e\u003cb data-path-to-node=\"17,2,0\" data-index-in-node=\"0\"\u003eAction:\u003c\/b\u003e Triggers the immediate \u003cb data-path-to-node=\"17,2,0\" data-index-in-node=\"31\"\u003erelease\u003c\/b\u003e (exocytosis) of stored GH vesicles by depolarizing the somatotroph via calcium influx.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,3,0\"\u003e\u003cb data-path-to-node=\"17,3,0\" data-index-in-node=\"0\"\u003eSelectivity:\u003c\/b\u003e Unlike older generations (GHRP-6\/GHRP-2), Ipamorelin is highly selective. It stimulates GH release \u003cb data-path-to-node=\"17,3,0\" data-index-in-node=\"112\"\u003ewithout\u003c\/b\u003e spiking ACTH (cortisol) or prolactin, ensuring clean research data unconfounded by stress hormones.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"18\"\u003e\n\u003ch3 data-path-to-node=\"19\"\u003e\u003cb data-path-to-node=\"19\" data-index-in-node=\"0\"\u003eChemical Specifications\u003c\/b\u003e\u003c\/h3\u003e\n\u003ctable data-path-to-node=\"20\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eComponent\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eKey Modification\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,1,0,0\"\u003e\u003cb data-path-to-node=\"20,1,0,0\" data-index-in-node=\"0\"\u003eCJC-1295 No DAC\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,1,1,0\"\u003e~3367.9 Da\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,1,2,0\"\u003eC152H252N44O42\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp data-path-to-node=\"20,1,3,0\"\u003e\u003cb data-path-to-node=\"20,1,3,0\" data-index-in-node=\"0\"\u003eD-Ala (Pos 2):\u003c\/b\u003e Blocks DPP-IV degradation.\u003c\/p\u003e\n\u003cbr data-path-to-node=\"20,1,3,1\"\u003e\n\u003cp data-path-to-node=\"20,1,3,2\"\u003e\u003cb data-path-to-node=\"20,1,3,2\" data-index-in-node=\"0\"\u003eGln (Pos 8):\u003c\/b\u003e Prevents deamidation.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,2,0,0\"\u003e\u003cb data-path-to-node=\"20,2,0,0\" data-index-in-node=\"0\"\u003eIpamorelin\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,2,1,0\"\u003e~711.9 Da\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,2,2,0\"\u003eC38H49N9O5\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan data-path-to-node=\"20,2,3,0\"\u003e\u003cb data-path-to-node=\"20,2,3,0\" data-index-in-node=\"0\"\u003eAib \u0026amp; D-2-Nal:\u003c\/b\u003e Structural constraints for high GHS-R1a affinity and stability.\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003chr data-path-to-node=\"21\"\u003e\n\u003ch3 data-path-to-node=\"22\"\u003e\u003cb data-path-to-node=\"22\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e1. Musculoskeletal Regeneration \u0026amp; Hypertrophy\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe GH\/IGF-1 axis is a primary driver of protein synthesis via the mTOR pathway. This blend is frequently utilized in research regarding:\u003c\/p\u003e\n\u003cul data-path-to-node=\"24\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"24,0,0\"\u003eActivation of satellite cells for muscle fiber repair.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"24,1,0\"\u003eNitrogen retention in catabolic states (e.g., sarcopenia).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"24,2,0\"\u003eCollagen synthesis for tendon and ligament connective tissue integrity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e2. Lipolysis \u0026amp; Metabolic Regulation\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGrowth hormone is a potent lipolytic agent. Research indicates that the pulsatile release generated by this blend is superior for fat loss compared to continuous \"bleed\" methods (like DAC variants), which can desensitize receptors.\u003c\/p\u003e\n\u003cul data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eVisceral Fat:\u003c\/b\u003e Specific targeting of visceral adipocytes which have high GH receptor density.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,1,0\"\u003e\u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"0\"\u003eInsulin Sensitivity:\u003c\/b\u003e Pulsatile administration mitigates the risk of insulin resistance often seen with chronic GH elevation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e3. Neuroprotection \u0026amp; Sleep Architecture\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGHRH is inherently sleep-promoting. Investigational protocols suggest that administration prior to sleep cycles may reinforce Slow-Wave Sleep (Deep Sleep), facilitating neurocognitive recovery and repair.\u003c\/p\u003e\n\u003chr data-path-to-node=\"28\"\u003e\n\u003ch3 data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003eState:\u003c\/b\u003e Lyophilized (Freeze-Dried) Cake.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 24 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,0\"\u003e\u003cb data-path-to-node=\"30,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e Use Bacteriostatic Water (0.9% Benzyl Alcohol). Inject diluent slowly down the side of the vial to avoid foaming. \u003cb data-path-to-node=\"30,2,0\" data-index-in-node=\"130\"\u003eDo not shake.\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,3,0\"\u003e\u003cb data-path-to-node=\"30,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Once reconstituted, store at 4°C (Refrigerator). Use within 28 days for optimal stability.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp\u003eFOR RESEARCH USE ONLY.\u003c\/p\u003e\n\u003cp\u003eThis product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47709264478422,"sku":"2XB-CJCIPA-55","price":37.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/2X-BLEND-CJC-1295-No-DAC-10mg-Ipamorelin-10mg.png?v=1768509803","url":"https:\/\/peptagon.com\/products\/cjc-1295-no-dac-ipamorelin-cjc-ipa","provider":"Peptagon","version":"1.0","type":"link"}