{"product_id":"ghk-cu-copper-tripeptide-1-research-peptide","title":"GHK-Cu Research Peptide – 50mg \/ 75mg \/ 100mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eGHK-Cu Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e Glycyl-L-Histidyl-L-Lysine (Complexed with Copper Ion) \u003cb data-path-to-node=\"14\" data-index-in-node=\"65\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Blue Cake) \u003cb data-path-to-node=\"14\" data-index-in-node=\"112\"\u003eMolecular Formula:\u003c\/b\u003e C14H24N6O4Cu \u003cb data-path-to-node=\"14\" data-index-in-node=\"144\"\u003ePurity:\u003c\/b\u003e \u0026gt;99% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"164\"\u003eContent:\u003c\/b\u003e Available in 50mg, 75mg, and 100mg vials\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eGHK-Cu\u003c\/b\u003e is a naturally occurring copper complex first isolated from human plasma. It functions as a powerful signaling peptide that declines significantly with age (from 200 ng\/mL at age 20 to 80 ng\/mL at age 60).\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eUnlike simple carrier peptides, GHK-Cu is a \u003cb data-path-to-node=\"18\" data-index-in-node=\"44\"\u003egenomic modulator\u003c\/b\u003e. Research utilizing the Broad Institute's Connectivity Map indicates it influences the expression of over 4,000 genes (~31% of the human genome), shifting gene signatures from a pathological state back to a healthier, regenerative baseline. It is the gold standard for research into skin remodeling, hair follicle stimulation, and wound healing.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The \"Reset\" Switch\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eGHK-Cu operates by coordinating copper (II) ions and delivering them into cells, where they act as cofactors for vital enzymes.\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eGenomic Regulation:\u003c\/b\u003e It resets the gene expression of the \u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"57\"\u003eUbiquitin-Proteasome System (UPS)\u003c\/b\u003e, enhancing the cell's ability to clear toxic proteins (upregulating 41 UPS genes).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eCollagen \u0026amp; Decorin:\u003c\/b\u003e It stimulates the synthesis of Collagen Types I and III. Uniquely, it also upregulates \u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"107\"\u003eDecorin\u003c\/b\u003e (by \u0026gt;300%), a proteoglycan that ensures collagen fibers form an organized lattice rather than disordered scar tissue.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eAntioxidant Defense:\u003c\/b\u003e Activates Superoxide Dismutase (SOD), neutralizing free radicals and reducing oxidative stress.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Dermatology \u0026amp; Wound Healing\u003c\/b\u003e GHK-Cu is extensively studied for its ability to tighten loose skin and accelerate healing.\u003c\/p\u003e\n\u003cul data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eRemodeling:\u003c\/b\u003e It modulates MMPs (Matrix Metalloproteinases) and TIMPs to remove damaged tissue and replace it with healthy ECM.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,1,0\"\u003e\u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"0\"\u003eClinical Efficacy:\u003c\/b\u003e In comparative studies, GHK-Cu reduced wrinkle depth by \u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"75\"\u003e32.8%\u003c\/b\u003e, outperforming other non-copper peptides like Matrixyl 3000.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e2. Trichology (Hair Growth)\u003c\/b\u003e Investigated as a potent hair growth stimulant.\u003c\/p\u003e\n\u003cul data-path-to-node=\"28\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,0,0\"\u003e\u003cb data-path-to-node=\"28,0,0\" data-index-in-node=\"0\"\u003eAngiogenesis:\u003c\/b\u003e Increases VEGF expression around the follicle, improving nutrient supply.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,1,0\"\u003e\u003cb data-path-to-node=\"28,1,0\" data-index-in-node=\"0\"\u003eFollicle Size:\u003c\/b\u003e Research indicates it enlarges follicle size and reverses miniaturization, pushing resting (telogen) follicles into the growth (anagen) phase faster than Minoxidil.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003e3. Oncology (Metastasis Suppression)\u003c\/b\u003e Paradoxically, while regenerative, GHK-Cu has been shown to reverse the gene signature of metastatic colon cancer. It induces apoptosis in malignant cells by upregulating \u003cb data-path-to-node=\"29\" data-index-in-node=\"208\"\u003ep27kip1\u003c\/b\u003e and \u003cb data-path-to-node=\"29\" data-index-in-node=\"220\"\u003eCaspase-3\u003c\/b\u003e, acting as a \"smart\" molecule that supports healthy cells while targeting damaged ones.\u003c\/p\u003e\n\u003chr data-path-to-node=\"30\"\u003e\n\u003ch3 data-path-to-node=\"31\"\u003e\u003cb data-path-to-node=\"31\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"32\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"32,0,0\"\u003e\u003cb data-path-to-node=\"32,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized \u003cb data-path-to-node=\"32,0,0\" data-index-in-node=\"28\"\u003eBlue\u003c\/b\u003e Powder. (The blue color is natural due to copper coordination).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"32,1,0\"\u003e\u003cb data-path-to-node=\"32,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 24 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"32,2,0\"\u003e\u003cb data-path-to-node=\"32,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"32,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"32,2,1,0,0\"\u003e\u003cb data-path-to-node=\"32,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Bacteriostatic Water or Sterile Saline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"32,2,1,1,0\"\u003e\u003cb data-path-to-node=\"32,2,1,1,0\" data-index-in-node=\"0\"\u003eSolubility:\u003c\/b\u003e Highly soluble (\u0026gt;50 mg\/mL).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"32,2,1,2,0\"\u003e\u003cb data-path-to-node=\"32,2,1,2,0\" data-index-in-node=\"0\"\u003eConcentration:\u003c\/b\u003e For standard 1-2% topical research solutions, dilute the 100mg vial into 5-10mL of solvent.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"32,3,0\"\u003e\u003cb data-path-to-node=\"32,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C (Refrigerator). Stable for ~1 month.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"33\"\u003e\n\u003ch3 data-path-to-node=\"34\"\u003e\u003cb data-path-to-node=\"34\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"35\"\u003e\u003cb data-path-to-node=\"35\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"50mg","offer_id":47710044618966,"sku":"GHKCU-50","price":29.0,"currency_code":"USD","in_stock":true},{"title":"75mg","offer_id":47710044651734,"sku":"GHKCU-75-6ML","price":37.0,"currency_code":"USD","in_stock":true},{"title":"100mg","offer_id":47710044684502,"sku":"GHKCU-100-6ML","price":44.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/Front_Back-GHK-Cu50mg.png?v=1779128552","url":"https:\/\/peptagon.com\/products\/ghk-cu-copper-tripeptide-1-research-peptide","provider":"Peptagon","version":"1.0","type":"link"}