{"product_id":"ghrp-6-ghs-r1a-research-peptide","title":"GHRP-6 Research Peptide – 5mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eGHRP-6 Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 \u003cb data-path-to-node=\"14\" data-index-in-node=\"42\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"84\"\u003eClass:\u003c\/b\u003e Growth Hormone Secretagogue (GHS) \u003cb data-path-to-node=\"14\" data-index-in-node=\"125\"\u003ePurity:\u003c\/b\u003e \u0026gt;98% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"145\"\u003eContent:\u003c\/b\u003e 5mg per vial\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eGHRP-6\u003c\/b\u003e is a synthetic hexapeptide and the first true Growth Hormone Secretagogue (GHS) developed. It acts as a potent agonist of the \u003cb data-path-to-node=\"17\" data-index-in-node=\"133\"\u003eGhrelin Receptor (GHS-R1a)\u003c\/b\u003e, mimicking the hunger hormone ghrelin to stimulate the release of Growth Hormone (GH) from the pituitary gland.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eUnlike newer, selective secretagogues (like Ipamorelin), GHRP-6 retains a broad pharmacological profile. It is renowned for its intense \u003cb data-path-to-node=\"18\" data-index-in-node=\"136\"\u003eorexigenic (appetite-stimulating)\u003c\/b\u003e effects and its secondary action on the \u003cb data-path-to-node=\"18\" data-index-in-node=\"210\"\u003eCD36 receptor\u003c\/b\u003e, which confers significant cytoprotective and anti-inflammatory properties in cardiac and gastric tissues.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The Dual-Pathway Agonist\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eGHRP-6 operates via distinct receptor interactions that drive both hormonal and survival signaling.\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eGHS-R1a Activation (GH Release):\u003c\/b\u003e Binds to receptors in the pituitary and hypothalamus, triggering the PLC-IP3 pathway. This causes a massive influx of calcium that releases stored Growth Hormone vesicles.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eCD36 Interaction (Cytoprotection):\u003c\/b\u003e Binds to the CD36 scavenger receptor on heart and endothelial cells. This activates the \u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"123\"\u003ePI3K\/Akt pathway\u003c\/b\u003e, increasing the Bcl-2\/Bax ratio to prevent apoptosis (cell death) during ischemic stress.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eHypothalamic Signaling:\u003c\/b\u003e Activates \u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"34\"\u003eNPY\/AgRP neurons\u003c\/b\u003e in the arcuate nucleus, driving a powerful hunger signal and metabolic shift toward anabolism.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Potent GH Secretion \u0026amp; Diagnostics\u003c\/b\u003e GHRP-6 is one of the most powerful GH releasers available.\u003c\/p\u003e\n\u003cul data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eDiagnostic Standard:\u003c\/b\u003e The combination of GHRH + GHRP-6 is the \"Gold Standard\" provocation test for diagnosing Adult GH Deficiency, capable of stimulating GH release even when other agents fail.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,1,0\"\u003e\u003cb data-path-to-node=\"26,1,0\" data-index-in-node=\"0\"\u003eSynergy:\u003c\/b\u003e Exhibits massive synergy when stacked with GHRH analogs (like CJC-1295), creating a GH pulse far greater than the sum of individual administrations.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e2. Appetite \u0026amp; Cachexia\u003c\/b\u003e Investigated for treating wasting conditions (cachexia).\u003c\/p\u003e\n\u003cul data-path-to-node=\"28\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,0,0\"\u003e\u003cb data-path-to-node=\"28,0,0\" data-index-in-node=\"0\"\u003eHyperphagia:\u003c\/b\u003e Induces rapid, intense hunger by mimicking ghrelin, making it a primary tool for reversing involuntary weight loss and anorexia in disease models.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003e3. Cardioprotection \u0026amp; Tissue Repair\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003eIschemia Reperfusion:\u003c\/b\u003e Reduces heart tissue damage following heart attacks by preventing mitochondrial collapse via the CD36 pathway.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003eGastric Protection:\u003c\/b\u003e Acts as a potent cytoprotectant in the stomach, preventing stress ulcers and accelerating gastric emptying (prokinetic effect) in models of diabetic gastroparesis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"33\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,0,0\"\u003e\u003cb data-path-to-node=\"33,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,1,0\"\u003e\u003cb data-path-to-node=\"33,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 36 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,0\"\u003e\u003cb data-path-to-node=\"33,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"33,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,0,0\"\u003e\u003cb data-path-to-node=\"33,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Bacteriostatic Water or Sterile Saline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,1,0\"\u003e\u003cb data-path-to-node=\"33,2,1,1,0\" data-index-in-node=\"0\"\u003eSolubility:\u003c\/b\u003e Highly soluble due to cationic residues.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,3,0\"\u003e\u003cb data-path-to-node=\"33,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C (Refrigerator). Use within 3-4 weeks.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"34\"\u003e\n\u003ch3 data-path-to-node=\"35\"\u003e\u003cb data-path-to-node=\"35\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"36\"\u003e\u003cb data-path-to-node=\"36\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47710089085142,"sku":"GHRP6-5","price":29.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/GHRP-6-5mg.png?v=1768509420","url":"https:\/\/peptagon.com\/products\/ghrp-6-ghs-r1a-research-peptide","provider":"Peptagon","version":"1.0","type":"link"}