{"product_id":"melanotan-ii-mt-ii-melanocortin-research-peptide","title":"Melanotan II Research Peptide – 10mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eMelanotan II Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2 (Cyclic Lactam) \u003cb data-path-to-node=\"14\" data-index-in-node=\"63\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"105\"\u003eClass:\u003c\/b\u003e Melanocortin Receptor Agonist \u003cb data-path-to-node=\"14\" data-index-in-node=\"142\"\u003ePurity:\u003c\/b\u003e \u0026gt;98% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"162\"\u003eContent:\u003c\/b\u003e 10mg per vial\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eMelanotan II (MT-II)\u003c\/b\u003e is a synthetic cyclic heptapeptide and a \"super-agonist\" of the melanocortin receptor system. It was originally developed as a tanning agent but is widely researched for its pleiotropic effects on sexual function and metabolism.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eUnlike native alpha-MSH, which degrades in minutes, MT-II incorporates a lactam bridge and D-amino acids that lock it into a bioactive conformation, making it highly resistant to enzymatic breakdown. It potently activates MC1R (pigmentation), MC3R\/MC4R (sexual desire\/metabolism), and MC5R.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The Pan-Agonist\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eMT-II operates via multiple G-protein coupled receptors to drive diverse physiological responses.\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eMC1R Activation (Pigmentation):\u003c\/b\u003e Binds to receptors on melanocytes, increasing intracellular cAMP. This upregulates MITF and Tyrosinase, driving the synthesis of \u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"161\"\u003eeumelanin\u003c\/b\u003e (photoprotective brown pigment) over pheomelanin.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eMC4R Activation (Libido):\u003c\/b\u003e Acts centrally in the hypothalamus (PVN\/MPOA) to trigger sexual desire and erectile function via dopamine and nitric oxide pathways. It is effective even in models of nerve damage.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eMetabolic Regulation:\u003c\/b\u003e Activation of hypothalamic MC4R suppresses appetite (anorexigenic) and increases energy expenditure via sympathetic nervous system stimulation of brown fat thermogenesis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Photoprotection \u0026amp; Tanning\u003c\/b\u003e MT-II is the benchmark for stimulating tanning without UV exposure.\u003c\/p\u003e\n\u003cul data-path-to-node=\"26\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eEumelanin Synthesis:\u003c\/b\u003e Research confirms it increases melanin density, providing biological protection against UV radiation (distinct from sunless tanners that only dye the skin).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e2. Sexual Function (ED \u0026amp; Libido)\u003c\/b\u003e Investigated as a potent initiator of sexual desire and erection.\u003c\/p\u003e\n\u003cul data-path-to-node=\"28\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"28,0,0\"\u003e\u003cb data-path-to-node=\"28,0,0\" data-index-in-node=\"0\"\u003eCentral Mechanism:\u003c\/b\u003e Unlike PDE5 inhibitors (Viagra) which act on blood flow, MT-II acts on the brain to increase \u003ci data-path-to-node=\"28,0,0\" data-index-in-node=\"112\"\u003edesire\u003c\/i\u003e and \u003ci data-path-to-node=\"28,0,0\" data-index-in-node=\"123\"\u003earousal\u003c\/i\u003e. Clinical trials showed erectile response in \u003cb data-path-to-node=\"28,0,0\" data-index-in-node=\"176\"\u003e85%\u003c\/b\u003e of men with ED.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003e3. Metabolism \u0026amp; Weight Loss\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003eFat Loss:\u003c\/b\u003e In animal models, MT-II causes significant weight loss by reducing food intake and preferentially burning visceral fat, even in diet-induced obesity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"33\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,0,0\"\u003e\u003cb data-path-to-node=\"33,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,1,0\"\u003e\u003cb data-path-to-node=\"33,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 12 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,0\"\u003e\u003cb data-path-to-node=\"33,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"33,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,0,0\"\u003e\u003cb data-path-to-node=\"33,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Bacteriostatic Water or Sterile Saline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,2,1,1,0\"\u003e\u003cb data-path-to-node=\"33,2,1,1,0\" data-index-in-node=\"0\"\u003eSolubility:\u003c\/b\u003e Highly soluble.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"33,3,0\"\u003e\u003cb data-path-to-node=\"33,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C (Refrigerator). Use within 3-4 weeks to prevent degradation. \u003cb data-path-to-node=\"33,3,0\" data-index-in-node=\"92\"\u003eAvoid freeze-thaw cycles.\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"34\"\u003e\n\u003ch3 data-path-to-node=\"35\"\u003e\u003cb data-path-to-node=\"35\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"36\"\u003e\u003cb data-path-to-node=\"36\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47712368066774,"sku":"MTII-10","price":32.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/Melanotan-II-10mg.png?v=1768511032","url":"https:\/\/peptagon.com\/products\/melanotan-ii-mt-ii-melanocortin-research-peptide","provider":"Peptagon","version":"1.0","type":"link"}