{"product_id":"semax-acth-4-10-analog-research-peptide","title":"Semax Research Peptide – 30mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eSemax Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP) \u003cb data-path-to-node=\"14\" data-index-in-node=\"48\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"90\"\u003eClass:\u003c\/b\u003e Nootropic \/ Neuroprotective Peptide \u003cb data-path-to-node=\"14\" data-index-in-node=\"133\"\u003ePurity:\u003c\/b\u003e \u0026gt;98% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"153\"\u003eContent:\u003c\/b\u003e 30mg per vial\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eSemax\u003c\/b\u003e is a synthetic heptapeptide derived from the ACTH(4-10) fragment. It was engineered at the Institute of Molecular Genetics (Russian Academy of Sciences) to retain the potent neurotropic effects of ACTH—such as improved learning and memory—without any hormonal or steroidogenic activity.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eThis \u003cb data-path-to-node=\"18\" data-index-in-node=\"5\"\u003e30mg High-Concentration Formulation\u003c\/b\u003e is designed for advanced research protocols, specifically those investigating acute neuroprotection (e.g., post-stroke or TBI models) where higher cumulative doses are required to modulate the brain's transcriptome and suppress inflammatory gene clusters.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The Genomic Modulator\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eSemax operates via rapid transcriptional and enzymatic regulation in the central nervous system.\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eNeurotrophic Upregulation:\u003c\/b\u003e Significantly increases the expression of \u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"69\"\u003eBDNF (Brain-Derived Neurotrophic Factor)\u003c\/b\u003e and \u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"114\"\u003eNGF (Nerve Growth Factor)\u003c\/b\u003e in the hippocampus and cortex. This promotes neuronal survival, synaptic plasticity, and axonal growth.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eTranscriptomic Reset:\u003c\/b\u003e In models of ischemia (stroke), Semax modulates the expression of over 1,500 genes. It specifically suppresses inflammatory gene clusters (e.g., \u003ci data-path-to-node=\"22,1,0\" data-index-in-node=\"167\"\u003eMmp9\u003c\/i\u003e, \u003ci data-path-to-node=\"22,1,0\" data-index-in-node=\"173\"\u003eNfkb\u003c\/i\u003e) while upregulating vascular and neurotransmitter genes, limiting the \"penumbra\" of damage.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eNeurotransmitter Balance:\u003c\/b\u003e Enhances dopaminergic and serotonergic signaling while inhibiting enkephalinases (enzymes that break down natural opioids), improving mood, focus, and pain tolerance.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Stroke \u0026amp; Traumatic Brain Injury (TBI)\u003c\/b\u003e Semax is a primary candidate for neuroprotection. Clinical and preclinical data indicate it reduces infarct volume by up to \u003cb data-path-to-node=\"25\" data-index-in-node=\"165\"\u003e25%\u003c\/b\u003e and accelerates neurological recovery when administered in the acute phase of injury.\u003c\/p\u003e\n\u003cp data-path-to-node=\"26\"\u003e\u003cb data-path-to-node=\"26\" data-index-in-node=\"0\"\u003e2. Cognitive Enhancement (Nootropic)\u003c\/b\u003e Investigated for its ability to improve memory formation, attention span, and learning efficiency. It is used in research models of ADHD and developmental delay to normalize behavioral responses and cognitive processing.\u003c\/p\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e3. Ophthalmology (Retinal Protection)\u003c\/b\u003e Studies show Semax improves retinal microcirculation and electrical sensitivity of the optic nerve, making it a valuable tool for research into optic neuropathy, glaucoma, and diabetic retinopathy.\u003c\/p\u003e\n\u003chr data-path-to-node=\"28\"\u003e\n\u003ch3 data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 24 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,0\"\u003e\u003cb data-path-to-node=\"30,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"30,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,1,0,0\"\u003e\u003cb data-path-to-node=\"30,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Sterile Water or Bacteriostatic Water.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,1,1,0\"\u003e\u003cb data-path-to-node=\"30,2,1,1,0\" data-index-in-node=\"0\"\u003eSolubility:\u003c\/b\u003e Highly soluble (\u0026gt;2mg\/mL).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,3,0\"\u003e\u003cb data-path-to-node=\"30,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C (Refrigerator). \u003cb data-path-to-node=\"30,3,0\" data-index-in-node=\"47\"\u003eUse within 14-21 days.\u003c\/b\u003e Semax degrades over time in solution; aliquoting and freezing is recommended for long-term experiments.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"33\"\u003e\u003cb data-path-to-node=\"33\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47712591118550,"sku":"SEMAX-30","price":50.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/Semax-30mg.png?v=1768507779","url":"https:\/\/peptagon.com\/products\/semax-acth-4-10-analog-research-peptide","provider":"Peptagon","version":"1.0","type":"link"}