{"product_id":"thymagen-thymomimetic-dipeptide-research-peptide","title":"Thymagen Research Peptide – 20mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eThymogen Peptide (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eSequence:\u003c\/b\u003e L-Glu-L-Trp (EW) \u003cb data-path-to-node=\"14\" data-index-in-node=\"27\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"69\"\u003eClass:\u003c\/b\u003e Thymic Bioregulator \/ Immunomodulator \u003cb data-path-to-node=\"14\" data-index-in-node=\"114\"\u003ePurity:\u003c\/b\u003e \u0026gt;98% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"134\"\u003eContent:\u003c\/b\u003e 20mg per vial\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003e\u003cb data-path-to-node=\"17\" data-index-in-node=\"0\"\u003eThymogen\u003c\/b\u003e is a synthetic dipeptide (Glutamic Acid - Tryptophan) developed as a bioregulator to mimic the natural signaling of the thymus gland. Originally isolated from thymic extracts, this stabilized dipeptide acts as a \"thymomimetic,\" signaling the maturation and differentiation of T-cells even when thymic function is compromised by age or stress.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eThymogen is unique in its ability to normalize immune function—boosting suppressed immunity while stabilizing hyper-inflammatory states—without the immunogenicity of larger proteins. It is widely researched for its role in reversing immunosenescence and modulating the innate immune response via Toll-like receptors.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The Immune Architect\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eThymogen operates at the genetic and cellular level to restore immune homeostasis.\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eT-Cell Maturation:\u003c\/b\u003e Stimulates the differentiation of hematopoietic stem cells into functional CD3+, CD4+, and CD8+ T-lymphocytes via the \u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"137\"\u003eNotch signaling pathway\u003c\/b\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eInnate Activation:\u003c\/b\u003e Upregulates the expression of \u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"49\"\u003eToll-like Receptors (TLR3, 7, 8, 9)\u003c\/b\u003e and cytoplasmic sensors (RIG-I), enhancing the body's ability to detect and respond to viral pathogens.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eEpigenetic Regulation:\u003c\/b\u003e Acts as a Khavinson peptide, penetrating the nucleus to modulate gene expression related to cytokine synthesis and DNA repair, effectively slowing the rate of thymic involution (atrophy).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Immunosenescence \u0026amp; Aging\u003c\/b\u003e Thymogen is a primary candidate for \"geroprotection\" research. Studies indicate it can restore T-cell populations in aged models, countering the natural decline of the immune system and improving resistance to infections.\u003c\/p\u003e\n\u003cp data-path-to-node=\"26\"\u003e\u003cb data-path-to-node=\"26\" data-index-in-node=\"0\"\u003e2. Viral Defense \u0026amp; Respiratory Health\u003c\/b\u003e Investigated for its virucidal properties and ability to prime the innate immune system. In vitro studies show it inhibits the replication of respiratory viruses (RSV, Influenza) by activating the MyD88\/IRAK1 signaling cascade.\u003c\/p\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e3. Autoimmunity \u0026amp; Inflammation\u003c\/b\u003e Research suggests Thymogen acts as an immunocorrector, normalizing the CD4\/CD8 ratio and suppressing excessive pro-inflammatory cytokines (TNF-alpha, IL-6) in conditions like chronic inflammation or autoimmune disorders.\u003c\/p\u003e\n\u003chr data-path-to-node=\"28\"\u003e\n\u003ch3 data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 36 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,0\"\u003e\u003cb data-path-to-node=\"30,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"30,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,1,0,0\"\u003e\u003cb data-path-to-node=\"30,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Bacteriostatic Water or Sterile Saline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,1,1,0\"\u003e\u003cb data-path-to-node=\"30,2,1,1,0\" data-index-in-node=\"0\"\u003eSolubility:\u003c\/b\u003e Highly soluble in water (\u0026gt;10mg\/mL).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,3,0\"\u003e\u003cb data-path-to-node=\"30,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C (Refrigerator). \u003cb data-path-to-node=\"30,3,0\" data-index-in-node=\"47\"\u003eUse within 2-4 weeks.\u003c\/b\u003e Avoid freeze-thaw cycles.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"33\"\u003e\u003cb data-path-to-node=\"33\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47712623853782,"sku":"THYMAGEN-20","price":38.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/Thymagen-20mg.png?v=1768508109","url":"https:\/\/peptagon.com\/products\/thymagen-thymomimetic-dipeptide-research-peptide","provider":"Peptagon","version":"1.0","type":"link"}