{"product_id":"thymosin-alpha-1-thymulin-complex-research-peptide","title":"Thymosin Alpha 1 + Thymulin Research Peptide Blend – 10mg \/ 6.4mg","description":"\u003ch4 data-path-to-node=\"13\"\u003e\u003cstrong\u003eThymosin Alpha 1 + Thymulin Complex (Lyophilized)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eComposition:\u003c\/b\u003e Thymosin Alpha 1 (10mg) \/ Thymulin (6.4mg) \u003cb data-path-to-node=\"14\" data-index-in-node=\"56\"\u003eFormat:\u003c\/b\u003e Sterile Lyophilized Powder (Vial) \u003cb data-path-to-node=\"14\" data-index-in-node=\"98\"\u003eRatio:\u003c\/b\u003e Optimized Synergistic Blend \u003cb data-path-to-node=\"14\" data-index-in-node=\"133\"\u003ePurity:\u003c\/b\u003e \u0026gt;98% (HPLC) \u003cb data-path-to-node=\"14\" data-index-in-node=\"153\"\u003eTotal Content:\u003c\/b\u003e 16.4mg per vial\u003c\/p\u003e\n\u003chr data-path-to-node=\"15\"\u003e\n\u003ch3 data-path-to-node=\"16\"\u003e\u003cb data-path-to-node=\"16\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"17\"\u003eThis \u003cb data-path-to-node=\"17\" data-index-in-node=\"5\"\u003eThymic Peptide Complex\u003c\/b\u003e combines two of the most potent bioregulators derived from the thymus gland: \u003cb data-path-to-node=\"17\" data-index-in-node=\"105\"\u003eThymosin Alpha 1 (TA1)\u003c\/b\u003e and \u003cb data-path-to-node=\"17\" data-index-in-node=\"132\"\u003eThymulin (FTS)\u003c\/b\u003e.\u003c\/p\u003e\n\u003cp data-path-to-node=\"18\"\u003eWhile TA1 acts as a powerful modulator of innate immunity via Toll-like receptors, Thymulin functions as a zinc-dependent neuroendocrine regulator that drives T-cell differentiation. This synergistic 10mg\/6.4mg formulation is designed to investigate the complete restoration of the thymic axis, addressing both immune competence and neuroendocrine homeostasis in models of aging and chronic infection.\u003c\/p\u003e\n\u003chr data-path-to-node=\"19\"\u003e\n\u003ch3 data-path-to-node=\"20\"\u003e\u003cb data-path-to-node=\"20\" data-index-in-node=\"0\"\u003eMechanism of Action: The Dual Thymic Axis\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"21\"\u003eThis blend targets two distinct but complementary pathways of immune regulation.\u003c\/p\u003e\n\u003cul data-path-to-node=\"22\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eThymosin Alpha 1 (The TLR Agonist):\u003c\/b\u003e Activates \u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"46\"\u003eTLR9\/TLR2\u003c\/b\u003e on dendritic cells, triggering the MyD88 signaling cascade. This primes the innate immune system to detect pathogens and tumor antigens without causing excessive inflammation.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eThymulin (The Zinc Sensor):\u003c\/b\u003e Requires zinc to become biologically active. Once complexed, it binds to receptors on T-cells to promote their maturation into functional CD4+ and CD8+ subsets. It also acts on the neuroendocrine system to reduce inflammation via \u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"258\"\u003ep38 MAPK inhibition\u003c\/b\u003e.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eSynergy:\u003c\/b\u003e Together, they restore the \"thymic microenvironment,\" reversing the effects of thymic involution (atrophy) and boosting the body's ability to fight chronic viral infections and autoimmunity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"23\"\u003e\n\u003ch3 data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e1. Immunosenescence \u0026amp; Aging\u003c\/b\u003e The decline of thymic function is a primary driver of aging. This complex is researched for its ability to restore the production of naive T-cells, reversing the \"biological clock\" of the immune system and improving vaccine response in the elderly.\u003c\/p\u003e\n\u003cp data-path-to-node=\"26\"\u003e\u003cb data-path-to-node=\"26\" data-index-in-node=\"0\"\u003e2. Chronic Viral Infections (Hep B\/C, HIV)\u003c\/b\u003e TA1 is a standard therapy for Hepatitis B\/C. The addition of Thymulin is investigated for its ability to further enhance T-cell reactivity and reverse immune exhaustion (PD-1 expression) in chronic viral models.\u003c\/p\u003e\n\u003cp data-path-to-node=\"27\"\u003e\u003cb data-path-to-node=\"27\" data-index-in-node=\"0\"\u003e3. Neuroinflammation \u0026amp; Pain\u003c\/b\u003e Thymulin possesses potent anti-inflammatory and analgesic properties in the central nervous system. It reduces glial cell activation and proinflammatory cytokines, offering potential neuroprotective benefits in neurodegenerative research.\u003c\/p\u003e\n\u003chr data-path-to-node=\"28\"\u003e\n\u003ch3 data-path-to-node=\"29\"\u003e\u003cb data-path-to-node=\"29\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"30\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Lyophilized (Freeze-Dried) White Powder.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003eStorage (Powder):\u003c\/b\u003e Store at -20°C (Freezer). Stable for up to 24 months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,0\"\u003e\u003cb data-path-to-node=\"30,2,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul data-path-to-node=\"30,2,1\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,1,0,0\"\u003e\u003cb data-path-to-node=\"30,2,1,0,0\" data-index-in-node=\"0\"\u003eSolvent:\u003c\/b\u003e Bacteriostatic Water or Sterile Saline.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,2,1,1,0\"\u003e\u003cb data-path-to-node=\"30,2,1,1,0\" data-index-in-node=\"0\"\u003eNote:\u003c\/b\u003e Thymulin activity is zinc-dependent; standard culture media usually contain sufficient zinc, but in vivo research may require monitoring zinc status.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"30,3,0\"\u003e\u003cb data-path-to-node=\"30,3,0\" data-index-in-node=\"0\"\u003eStorage (Liquid):\u003c\/b\u003e Store at 4°C (Refrigerator). \u003cb data-path-to-node=\"30,3,0\" data-index-in-node=\"47\"\u003eUse within 21 days.\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"31\"\u003e\n\u003ch3 data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"33\"\u003e\u003cb data-path-to-node=\"33\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47712651739350,"sku":"TA1THY-16.4","price":100.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/Thymosin-Alpha-1-Complex-Thymulin-10mg-6.4mg.png?v=1768508198","url":"https:\/\/peptagon.com\/products\/thymosin-alpha-1-thymulin-complex-research-peptide","provider":"Peptagon","version":"1.0","type":"link"}