{"product_id":"vip-bpc-157-oral-peptide-blend","title":"VIP + BPC-157 Research Tablets – 2mg \/ 500mcg – 30 Count","description":"\u003ch4 data-path-to-node=\"11\"\u003e\u003cstrong\u003eVIP \/ BPC-157: The Immunomodulatory \u0026amp; Regenerative Matrix\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-path-to-node=\"12\"\u003e\u003cb data-path-to-node=\"12\" data-index-in-node=\"0\"\u003eComposition:\u003c\/b\u003e Vasoactive Intestinal Peptide (2 mg) \/ BPC-157 (500 mcg) \u003cb data-path-to-node=\"12\" data-index-in-node=\"70\"\u003eFormat:\u003c\/b\u003e Oral Tablets \u003cb data-path-to-node=\"12\" data-index-in-node=\"91\"\u003eClass:\u003c\/b\u003e Pleiotropic Peptide Blend \u003cb data-path-to-node=\"12\" data-index-in-node=\"124\"\u003ePrimary Targets:\u003c\/b\u003e VPAC1\/2 Receptors, FAK-Paxillin Pathway, NF-κB Inhibition\u003c\/p\u003e\n\u003chr data-path-to-node=\"13\"\u003e\n\u003ch3 data-path-to-node=\"14\"\u003e\u003cb data-path-to-node=\"14\" data-index-in-node=\"0\"\u003eProduct Overview\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"15\"\u003eThis \u003cb data-path-to-node=\"15\" data-index-in-node=\"5\"\u003eVIP \/ BPC-157 Blend\u003c\/b\u003e represents a sophisticated experimental architecture designed to address the \"Inflammation-Regeneration Paradox.\" By combining a high-dose neuro-immunomodulator (VIP) with a cytoprotective structural organizer (BPC-157), this formulation targets two distinct biological axes simultaneously.\u003c\/p\u003e\n\u003cul data-path-to-node=\"16\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"16,0,0\"\u003e\u003cb data-path-to-node=\"16,0,0\" data-index-in-node=\"0\"\u003eThe VIP Component (2 mg):\u003c\/b\u003e A massive supraphysiological dose designed to saturate local proteolytic enzymes and target the \u003cb data-path-to-node=\"16,0,0\" data-index-in-node=\"122\"\u003eGut-Associated Lymphoid Tissue (GALT)\u003c\/b\u003e. This strategy aims to induce oral tolerance and modulate systemic inflammation via the enteric nervous system.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"16,1,0\"\u003e\u003cb data-path-to-node=\"16,1,0\" data-index-in-node=\"0\"\u003eThe BPC-157 Component (500 mcg):\u003c\/b\u003e A stable, gastric-resistant pentadecapeptide that acts as the regenerative backbone. It drives structural repair, collagen organization, and angiogenesis, ensuring that the anti-inflammatory environment created by VIP is utilized for tissue reconstruction.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"17\"\u003e\n\u003ch3 data-path-to-node=\"18\"\u003e\u003cb data-path-to-node=\"18\" data-index-in-node=\"0\"\u003eMechanism of Action: The \"Brake and Accelerator\" Synergy\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"19\"\u003eThis blend utilizes complementary signaling pathways to optimize the healing environment:\u003c\/p\u003e\n\u003cul data-path-to-node=\"20\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"20,0,0\"\u003e\u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"0\"\u003eVIP (The Anti-Inflammatory Brake):\u003c\/b\u003e Activates the \u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"49\"\u003ecAMP-PKA-CREB\u003c\/b\u003e pathway and directly inhibits \u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"93\"\u003eNF-κB\u003c\/b\u003e. By preventing the translocation of NF-κB to the nucleus, VIP suppresses the \"cytokine storm\" (TNF-α, IL-6) that often stalls healing in chronic wounds and autoimmune conditions.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"20,1,0\"\u003e\u003cb data-path-to-node=\"20,1,0\" data-index-in-node=\"0\"\u003eBPC-157 (The Regenerative Accelerator):\u003c\/b\u003e Once inflammation is controlled, BPC-157 activates the \u003cb data-path-to-node=\"20,1,0\" data-index-in-node=\"95\"\u003eFAK-Paxillin\u003c\/b\u003e pathway to drive fibroblast migration and the \u003cb data-path-to-node=\"20,1,0\" data-index-in-node=\"154\"\u003eVEGFR2-Akt-eNOS\u003c\/b\u003e axis to promote angiogenesis. This ensures a robust blood supply and the organized deposition of collagen types I and III.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"20,2,0\"\u003e\u003cb data-path-to-node=\"20,2,0\" data-index-in-node=\"0\"\u003eThe Gut-Brain Axis:\u003c\/b\u003e Both peptides modulate the enteric nervous system. VIP regulates epithelial barrier integrity and secretion, while BPC-157 repairs physical defects (ulcers, fistulas) and protects neurons from oxidative stress.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"21\"\u003e\n\u003ch3 data-path-to-node=\"22\"\u003e\u003cb data-path-to-node=\"22\" data-index-in-node=\"0\"\u003eKey Research Applications\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"23\"\u003e\u003cb data-path-to-node=\"23\" data-index-in-node=\"0\"\u003e1. Gastrointestinal Pathology (IBD \u0026amp; Fistulas)\u003c\/b\u003e Investigated for its ability to heal complex gut injuries. Research shows BPC-157 achieves \u003cb data-path-to-node=\"23\" data-index-in-node=\"138\"\u003e100% closure of gastrocutaneous fistulas\u003c\/b\u003e in animal models, while VIP reduces colonic inflammation and restores epithelial barrier function in colitis models.\u003c\/p\u003e\n\u003cp data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003e2. Musculoskeletal Repair (Tendons \u0026amp; Ligaments)\u003c\/b\u003e The blend is studied for its capacity to improve load-to-failure strength in healing tendons. BPC-157 promotes the alignment of collagen fibers, while VIP prevents the excessive, disorganized scarring (fibrosis) often driven by chronic inflammation.\u003c\/p\u003e\n\u003cp data-path-to-node=\"25\"\u003e\u003cb data-path-to-node=\"25\" data-index-in-node=\"0\"\u003e3. Pulmonary \u0026amp; Vascular Health\u003c\/b\u003e VIP is a potent vasodilator and anti-fibrotic agent in the lung. Research indicates it can reduce pulmonary vascular resistance and mitigate fibrosis in bleomycin-induced models. BPC-157 supports this by normalizing nitric oxide levels and protecting endothelial function.\u003c\/p\u003e\n\u003cp data-path-to-node=\"26\"\u003e\u003cb data-path-to-node=\"26\" data-index-in-node=\"0\"\u003e4. Systemic Autoimmunity\u003c\/b\u003e By targeting the GALT, high-dose oral VIP is researched for its ability to induce regulatory T-cells (Tregs) and shift the immune response away from a pro-inflammatory Th1 profile, offering potential in models of rheumatoid arthritis and multiple sclerosis.\u003c\/p\u003e\n\u003chr data-path-to-node=\"27\"\u003e\n\u003ch3 data-path-to-node=\"28\"\u003e\u003cb data-path-to-node=\"28\" data-index-in-node=\"0\"\u003eStorage \u0026amp; Handling\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"29\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"29,0,0\"\u003e\u003cb data-path-to-node=\"29,0,0\" data-index-in-node=\"0\"\u003ePhysical State:\u003c\/b\u003e Oral research tablets.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"29,1,0\"\u003e\u003cb data-path-to-node=\"29,1,0\" data-index-in-node=\"0\"\u003eStorage:\u003c\/b\u003e Store in a cool, dry place away from direct sunlight and moisture.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"29,2,0\"\u003e\u003cb data-path-to-node=\"29,2,0\" data-index-in-node=\"0\"\u003eStability:\u003c\/b\u003e BPC-157 is inherently stable in gastric juice. The high dose of VIP compensates for enzymatic degradation, but the tablets should be kept desiccated to maintain potency.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr data-path-to-node=\"30\"\u003e\n\u003ch3 data-path-to-node=\"31\"\u003e\u003cb data-path-to-node=\"31\" data-index-in-node=\"0\"\u003eDisclaimer\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eFOR RESEARCH USE ONLY.\u003c\/b\u003e This product is a chemical compound intended strictly for laboratory research and development. It is not approved by the FDA for clinical use, diagnostics, or therapeutic procedures in humans or animals. The physiological and toxicological properties of this chemical have not been fully investigated.\u003c\/p\u003e","brand":"Peptagon","offers":[{"title":"Default Title","offer_id":47712776552662,"sku":"VIP-BPC-2-5x30","price":144.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0783\/3085\/5638\/files\/VIP_2mg_-BPC-157_500mcg_x30-Tablets_1.png?v=1768849935","url":"https:\/\/peptagon.com\/products\/vip-bpc-157-oral-peptide-blend","provider":"Peptagon","version":"1.0","type":"link"}